News tagged with nuclear receptor

Nuclear hormone receptors, microRNAs form developmental switch

A particular nuclear hormone receptor called DAF-12 and molecules called microRNAs in the let-7 family form a molecular switch that encourages cells in the larvae of a model worm to shift to a more developed state, said a ...

Medicine & Health / Medical research

created Apr 02, 2009 | popularity 5 / 5 (1) | comments 0

New concoction reprograms differentiated cells into pluripotent stem cells

In the new issue of the journal Cell Stem Cell, Singapore scientists report the surprising discovery that a novel transcription factor, Nr5a2, can replace one of the classical reprogramming factors, Oct 4, to significantly increa ...

Biology / Cell & Microbiology

created Jan 21, 2010 | popularity 5 / 5 (1) | comments 0

Nuclear receptors reveal possible interventions for cancer, obesity

Research with significant implications in the treatment and intervention of cancer and obesity has been published recently in two prestigious journals by University of Houston (UH) biochemist Dr. Jan-Ake Gustafsson.

Chemistry / Biochemistry

created Jan 10, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Protein structures give disease clues

Using some of the most powerful nuclear magnetic resonance equipment available, researchers at the University of California, Davis, are making discoveries about the shape and structure of biological molecules ...

Chemistry / Biochemistry

created Feb 01, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Latest epidemic? High cholesterol, obesity in fruit flies

How do fruit flies get high cholesterol and become obese? The same way as people do - by eating a diet that's too rich in fats.

Biology / Cell & Microbiology

created Dec 02, 2009 | popularity 4 / 5 (1) | comments 0

Turning a painkiller into a cancer killer

Without knowing exactly why, scientists have long observed that people who regularly take non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin have lower incidences of certain types of cancer. Now, in a study appearing ...

Medicine & Health / Cancer

created Jun 14, 2010 | popularity 4 / 5 (1) | comments 0

Keeping retinoic acid in check

Neurobiologists from the Friedrich Miescher Institute for Biomedical Research (FMI) of the Novartis Research Foundation are the first to describe a mechanism that controls the synthesis of retinoic acid in ...

Medicine & Health / Medical research

created Apr 19, 2011 | popularity 4 / 5 (1) | comments 0