News tagged with nuclear receptor
Protein structures give disease clues
Using some of the most powerful nuclear magnetic resonance equipment available, researchers at the University of California, Davis, are making discoveries about the shape and structure of biological molecules ...
Feb 01, 2012 |
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Nuclear receptors battle it out during metamorphosis in new fruit fly model
Growing up just got more complicated. Thomas Jefferson University biochemistry researchers have shown for the first time that the receptor for a major insect molting hormone doesn't activate and repress genes ...
Oct 06, 2011 |
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Nuclear receptors reveal possible interventions for cancer, obesity
Research with significant implications in the treatment and intervention of cancer and obesity has been published recently in two prestigious journals by University of Houston (UH) biochemist Dr. Jan-Ake Gustafsson.
Jan 10, 2011 |
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Blocking nuclear receptor may cut off tumor blood supply
A new method of blocking the genesis of blood vessels that feed tumors may start with the nuclear receptor COUP-TFII (chicken ovalbumin upstream promoter-transcription factor II), said a pair of Baylor College of Medicine ...
Jan 11, 2010 |
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Latest epidemic? High cholesterol, obesity in fruit flies
How do fruit flies get high cholesterol and become obese? The same way as people do - by eating a diet that's too rich in fats.
Dec 02, 2009 |
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Keeping retinoic acid in check
Neurobiologists from the Friedrich Miescher Institute for Biomedical Research (FMI) of the Novartis Research Foundation are the first to describe a mechanism that controls the synthesis of retinoic acid in ...
Medicine & Health / Medical research
Apr 19, 2011 |
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Cell study finds receptor can fight tamoxifen-resistant breast cancer cells
A receptor that is present in the nucleus of cells can, when activated, slow the growth of tamoxifen-resistant breast cancer cells, a new study found. The study built on the recent discovery that farnesoid X receptor (FXR) ...
Apr 27, 2010 |
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Scientists identify new mechanism regulating daily biological rhythms
Scientists from the Florida campus of The Scripps Research Institute have identified for the first time a novel mechanism that regulates circadian rhythm, the master clock that controls the body's natural 24-hour physiological ...
Nov 11, 2010 |
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Gene information predicts survival time, possible new treatment options for lung-cancer patients
Researchers at UT Southwestern Medical Center have discovered sets of genes active in cancer cells and normal tissue that predict survival time and potential new treatments for patients with non-small cell lung cancer.
Dec 14, 2010 |
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Turning a painkiller into a cancer killer
Without knowing exactly why, scientists have long observed that people who regularly take non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin have lower incidences of certain types of cancer. Now, in a study appearing ...
Jun 14, 2010 |
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Scientists identify first synthetic activator of two critical proteins
Scientists from the Florida campus of The Scripps Research Institute have identified a novel synthetic activator of a pair of proteins that belong to a protein family playing key roles in human metabolism and immune function. ...
Nov 19, 2010 |
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RXR activation -- hope for new Parkinson's disease treatment
Following up on their previous work showing the rescue of dopamine neurons by chemicals that interact with the retinoid X receptor (RXR), researchers have now investigated the potential of these chemicals, known as RXR ligands, ...
Medicine & Health / Neuroscience
Dec 11, 2009 |
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Nuclear hormone receptors, microRNAs form developmental switch
A particular nuclear hormone receptor called DAF-12 and molecules called microRNAs in the let-7 family form a molecular switch that encourages cells in the larvae of a model worm to shift to a more developed state, said a ...
Medicine & Health / Medical research
Apr 02, 2009 |
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Study indicates vitamin A plays key role in the human body
In a recently-published study mapping the structure and function of the so-called "orphan" nuclear receptor TR4, Van Andel Research Institute (VARI) investigators suggest that Vitamin A may play a more direct role than ...
Medicine & Health / Medical research
Mar 17, 2011 |
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New concoction reprograms differentiated cells into pluripotent stem cells
In the new issue of the journal Cell Stem Cell, Singapore scientists report the surprising discovery that a novel transcription factor, Nr5a2, can replace one of the classical reprogramming factors, Oct 4, to significantly increa ...
Jan 21, 2010 |
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