Related topics: high blood pressure · blood vessels

Heavy nitrogen molecules reveal planetary-scale tug-of-war

Nature whispers its stories in a faint molecular language, and Rice University scientist Laurence Yeung and colleagues can finally tell one of those stories this week, thanks to a one-of-a-kind instrument that allowed them ...

Curiosity rover finds biologically useful nitrogen on Mars

A team using the Sample Analysis at Mars (SAM) instrument suite aboard NASA's Curiosity rover has made the first detection of nitrogen on the surface of Mars from release during heating of Martian sediments.

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Nitric oxide

Nitric oxide or nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals, including humans, and is an extremely important intermediate in the chemical industry. It is also an air pollutant produced by cigarette smoke, automobile engines and power plants.

NO is an important messenger molecule involved in many physiological and pathological processes within the mammalian body both beneficial and detrimental. Appropriate levels of NO production are important in protecting an organ such as the liver from ischemic damage. However sustained levels of NO production result in direct tissue toxicity and contribute to the vascular collapse associated with septic shock, whereas chronic expression of NO is associated with various carcinomas and inflammatory conditions including juvenile diabetes, multiple sclerosis, arthritis and ulcerative colitis.

Nitric oxide should not be confused with nitrous oxide (N2O), a general anaesthetic and greenhouse gas, or with nitrogen dioxide (NO2) which is another air pollutant. The nitric oxide molecule is a free radical, which is relevant to understanding its high reactivity.

Despite being a simple molecule, NO is a fundamental player in the fields of neuroscience, physiology, and immunology, and was proclaimed “Molecule of the Year” in 1992.

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