News tagged with nijmegen breakage syndrome
Study shows how defective DNA repair triggers 2 neurological diseases
Scientists at St. Jude Children's Research Hospital have teased apart the biological details distinguishing two related neurological diseases—ataxia telangiectasia-like disease (ATLD) and Nijmegen breakage syndrome (NBS).
Jan 15, 2009 |
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Scientists find missing puzzle piece of powerful DNA repair complex
Researchers at The Scripps Research Institute have found, crystallized, and biologically characterized a poorly defined component of a key molecular complex that helps people to avoid cancer, but that also ...
Oct 01, 2009 |
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Protein's essential role in repairing damaged cells revealed
University of Michigan researchers have discovered that a key protein in cells plays a critical role in not one, but two processes affecting the development of cancer.
Biology /
Jan 06, 2009 |
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First glimpse of a key DNA repair protein at work
Repairing breaks in the two strands of the DNA double helix is critical for avoiding cancer. In humans and other organisms, a molecular machine called the MRN complex is responsible for finding and signaling ...
Biology /
Oct 03, 2008 |
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Protein 'chatter' linked to cancer activation
Scientists have found the existence of cross-talk between human chromosome ends and the protein complexes central to the stability of the entire human genome, a “chat” that contributes to cancer development.
Aug 13, 2007 |
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DNA repair proteins monitored at double-strand break
Investigators at St. Jude Children's Research Hospital had a molecule’s eye view of the human cell’s DNA repair kit as it assembled on a double-strand break to link together the broken ends. Double-strand breaks are ruptures ...
Biology /
May 09, 2007 |
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