Biologists reveal novel drug binding site in NMDA receptor subunit

Structural biologists at Cold Spring Harbor Laboratory (CSHL) have obtained a precise molecular map of the binding site for an allosteric inhibitor in a subtype of the NMDA (N-methyl-D-aspartate) receptor, which is commonly ...

Molecular architecture of key NMDA receptor subunit revealed

Structural biologists at Cold Spring Harbor Laboratory (CSHL) in collaboration with colleagues at Emory University have determined the molecular structure of a key portion, or subunit, of a receptor type commonly expressed ...

Researchers get a grip on nervous system's receptors

A digital signal processing technique long used by statisticians to analyze data is helping Houston scientists understand the roots of memory and learning, Alzheimer's and Parkinson's diseases and stroke.

How do organisms make dietary choices?

When given a choice, organisms will choose a diet that maintains a nutritional balance in tune with their needs. That choice, studied in fruit flies for the first time, is regulated by activity in a molecular pathway involved ...

Tryptophan-enriched diet reduces pig aggression

Feeding the amino acid tryptophan to young female pigs as part of their regular diet makes them less aggressive and easier to manage, according to a study by Agricultural Research Service (ARS) scientists and cooperators.

The mathematics behind a good night's sleep

Why can't I fall asleep? Will this new medication keep me up all night? Can I sleep off this cold? Despite decades of research, answers to these basic questions about one of our most essential bodily functions remain exceptionally ...

When cells run out of fuel

Parkinson's disease is caused by the degeneration of neurons in the midbrain. The mechanisms leading to the loss of these neurons, however, are largely unknown. Recent research revealed that about ten per cent of cases are ...

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