News tagged with neuron death

Scientists identify protein form linked to Huntington's disease

Scientists at the Gladstone Institutes have discovered how a form of the protein linked to Huntington's disease influences the timing and severity of its symptoms, offering new avenues for treating not only this disease, ...

Chemistry / Biochemistry

created Oct 30, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Alzheimer’s Findings Resolve Dispute Over How Disease Kills Brain Cells

(PhysOrg.com) -- For a decade, Alzheimer's disease researchers have been entrenched in debate about one of the mechanisms believed to be responsible for brain cell death and memory loss in the illness.

Medicine & Health / Neuroscience

created Apr 15, 2009 | popularity 4.2 / 5 (6) | comments 0

Scientists discover new direction in Alzheimer's research

In what they are calling a new direction in the study of Alzheimer's disease, UC Santa Barbara scientists have made an important finding about what happens to brain cells that are destroyed in Alzheimer's ...

Chemistry / Biochemistry

created Jun 06, 2011 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Parkinson's: Neurons destroyed by 3 simultaneous strikes

In a study that reveals the clearest picture to date of neuron death in Parkinson's disease, researchers at Columbia University Medical Center have found that a trio of culprits acting in concert is responsible for killing ...

Medicine & Health / Neuroscience

created Apr 29, 2009 | popularity 5 / 5 (1) | comments 0

Unearthing a pathway to brain damage

Neuroscientists have long suspected that abnormal calcium signaling and accumulation of misfolded proteins cause an intracellular membrane-bound organelle called the endoplasmic reticulum (ER) to trigger the ...

Medicine & Health / Neuroscience

created Feb 25, 2011 | popularity not rated yet | comments 0

Genetic change prevents cell death in mouse model of Parkinson's disease

(PhysOrg.com) -- By shifting a normal protective mechanism into overdrive, a University of Wisconsin-Madison scientist has completely shielded mice from a toxic chemical that would otherwise cause Parkinson's ...

Medicine & Health / Medical research

created Feb 02, 2009 | popularity 5 / 5 (1) | comments 0

Novel method results in promising drugs for Huntington's disease therapeutics

Huntington's disease (HD) is an incurable progressive neurodegenerative genetic disorder which affects motor coordination and leads to cognitive decline and dementia.

Medicine & Health / Medical research

created Jan 26, 2011 | popularity 4.7 / 5 (3) | comments 0

Matrix fragments trigger fatal excitement

Shredded extracellular matrix (ECM) is toxic to neurons. Chen et al. reveal a new mechanism for how ECM demolition causes brain damage. The study will appear in the December 29, 2008 issue of The Journal of ...

Biology /

created Dec 29, 2008 | popularity 5 / 5 (4) | comments 0

New insight into neuronal survival after brain injury

A new study identifies a molecule that is a critical regulator of neuron survival after ischemic brain injury. The research, published by Cell Press in the January 13 issue of the journal Neuron, may lead to new therapies that r ...

Medicine & Health / Neuroscience

created Jan 12, 2011 | popularity 5 / 5 (1) | comments 0

Protein may advance Parkinson's by preventing neurons from clearing debris

A protein linked to Parkinson's disease may cause neurodegeneration by inhibiting autophagy -- the process in which cells digest some of their contents -- according to a study in the September 20 issue of the Journal of Ce ...

Biology / Cell & Microbiology

created Sep 20, 2010 | popularity not rated yet | comments 0

Getting off tract: Polyglutamine disease involves other regions of protein

Many genes code for proteins that have a "polyglutamine tract," several glutamine amino acid residues in a row. Nine inherited neurodegenerative diseases, including Huntington's disease and spinocerebellar ataxia type 1 (SCA1), ...

Medicine & Health / Neuroscience

created Sep 22, 2010 | popularity not rated yet | comments 0

Searching for brain's defenses to ward off infections, prevent memory loss

Researchers at the Case Western Reserve University School of Dental Medicine and School of Medicine will look for evidence within the brain for human beta defensin peptide function -- proteins important to the peripheral ...

Medicine & Health / Medical research

created Apr 07, 2010 | popularity not rated yet | comments 0

Scientists discover how neuroglobin protects against Alzheimer's

A team of scientists at the University of California, Davis and the University of Auckland has discovered that neuroglobin may protect against Alzheimer's disease by preventing brain neurons from dying in response to natural ...

Medicine & Health / Neuroscience

created Aug 02, 2010 | popularity 5 / 5 (1) | comments 0

Identification of a gene essential to newborn babies' first breath

How do mammals prepare themselves in utero for a radical modification to their respiration at the time of birth, when they move abruptly from an aquatic medium to air?

Medicine & Health / Neuroscience

created Jul 21, 2010 | popularity not rated yet | comments 0

Humanin peptide linked to neuronal cell survival and regulation of glucose metabolism

Recent studies have shown that the mitochondrial peptide Humanin (HN) protects against neuronal cell death such as happens in Alzheimer's disease. Now, in a study presented April 22 at Experimental Biology 2009 in New Orleans, ...

Biology / Cell & Microbiology

created Apr 22, 2009 | popularity 5 / 5 (1) | comments 0