An enzyme called MARK2 has been identified as a key stress-response switch in cells in a study by researchers at Johns Hopkins Bloomberg School of Public Health. Overactivation of this type of stress response is a possible ...
Molecular & Computational biology
Mar 11, 2021
0
227
In a recent paper published in the Journal of Biological Chemistry Yuna Ayala, Ph.D., assistant professor of biochemistry and molecular biology at Saint Louis University, and her research team made advances in understanding ...
Biochemistry
Apr 19, 2017
1
12
SUNY Downstate scientist Ilham Muslimov, MD, PhD, along with senior author Henri Tiedge, PhD, professor of physiology and pharmacology and of neurology, published a study suggesting that cellular dysregulation associated ...
Cell & Microbiology
Sep 7, 2011
0
0
Strict regulation of axon branching and synapse formation is critical for the correct development of the embryonic nervous system, and dysfunction in these processes can lead to neurodevelopmental and neurodegenerative disorders. ...
Cell & Microbiology
Feb 7, 2014
0
0
Researchers have identified a protein complex that marks misfolded proteins, stops them from interacting with other proteins in the cell, and directs them toward disposal. In collaboration with the neurology department at ...
Cell & Microbiology
Mar 27, 2019
0
40
Researchers from the Universities of Konstanz (Germany), Leeds (U.K.) and Stanford (U.S.) have discovered that the nascent polypeptide-associated complex (NAC) prevents the aggregation of proteins associated with several ...
Cell & Microbiology
Apr 11, 2019
0
50
Cells have two chances to fix the same mistake in their protein-making process instead of just one - a so-called proofreading step - that had previously been identified, according to new research.
Cell & Microbiology
Mar 12, 2009
4
0
Massachusetts General Hospital (MGH) investigators have discovered the mechanism by which cells sense dysfunction of the proteasome—a cellular component that degrades unneeded or defective proteins—and respond in a previously ...
Molecular & Computational biology
Apr 18, 2019
0
16
In a finding that has important ramifications for neurodegenerative disorders such as Alzheimer's disease, RIKEN researchers have discovered how three chaperone molecules in yeast cells work together to break up beta-sheet-rich ...
Biochemistry
May 26, 2022
0
91
A new study from researchers at Karolinska Institutet published in Science Advances show that inactivation of a protein complex that controls gene repression leads to loss of neuronal identity of dopamine-producing cells ...
Cell & Microbiology
Aug 29, 2022
0
72
