Like cats, human cells have a finite number of lives-once they divide a certain number of times (thankfully, more than nine) they change shape, slow their pace, and eventually stop dividing, a phenomenon called ...
Oct 03, 2010
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One third of the world's population is infected with Mycobacterium tuberculosis (MTB), which leads to tuberculosis (TB), a leading cause of death world-wide. A new discovery, led by a team of researchers from Case Western ...
Sep 09, 2010
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A key step in understanding the origins of familial breast cancer has been made by two teams of scientists at the University of California, Davis. The researchers have purified, for the first time, the protein produced by ...
Aug 22, 2010
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(PhysOrg.com) -- A research team has made precise measurements of where and how RNA polymerase encounters obstacles while it reads nucleosomal DNA.
May 14, 2010
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Like a film director cutting out extraneous footage to create a blockbuster, the cellular machine called the spliceosome snips out unwanted stretches of genetic material and joins the remaining pieces to fashion a template ...
Mar 21, 2010
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(PhysOrg.com) -- A Yale research team led by Nobel laureate Thomas A. Steitz has discovered how a family of tuberculosis-fighting antibiotics combats the deadly disease, a finding that may lead to new ways ...
Feb 15, 2010
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Researchers at the University of Minnesota have discovered a molecular security system in human cells that deactivates and degrades foreign DNA. This discovery could open the door to major improvements in genetic engineering ...
Jan 10, 2010
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Researchers at Emory University School of Medicine have determined the structures of two enzymes that customize histones, the spool-like proteins around which DNA coils inside the cell.
Dec 20, 2009
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Imagine a huge spool of film containing thousands of sequences of random scenes. Without a talented editor, a screening would have no meaning.
Dec 14, 2009
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Researchers at The Scripps Research Institute have solved a 10-year-old mystery of how a single protein from an ancient family of enzymes can have two completely distinct roles in the body. In addition to providing guidance ...
Dec 13, 2009
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Scientists have known for a long time that when DNA is damaged, a key enzyme sets off a cellular "alarm bell" to alert the cell to start the repair process, but until recently little was known about how the cell detects and ...
Aug 13, 2009
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As the body creates antibodies to fight invaders, a three-protein DNA repair complex called MRN is crucial for a normal gene-shuffling process to proceed properly, University of Michigan research shows.
Aug 05, 2009
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In a paper published in the early online version of Nature Structural and Molecular Biology, researchers at the University of Pittsburgh School of Medicine deconstruct the first steps in an intricate molecular dance that m ...
Mar 08, 2009
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Researchers at the Dana-Farber Cancer Institute, Burnham Institute for Medical Research and the Centers for Disease Control and Prevention have reported the identification of human monoclonal antibodies (mAb) that neutralize ...
Feb 22, 2009
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(PhysOrg.com) -- Anyone who has ever battled a stuck zipper knows it's a good idea to see what's stuck, where and how badly -- and then to pull hard. A Cornell research team's experiments involve the "unzipping" ...
Jan 28, 2009
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