Current drugs block the actions of only about a quarter of known disease-causing proteins, but Yale University researchers have developed a technology capable of not just inhibiting, but destroying every protein it targets.
Biochemistry
Jun 11, 2015
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86
Enzymes called protein kinases modulate cellular activities in virtually every organism. They switch other proteins off or on by tacking on phosphate chemical groups—a process known as phosphorylation—to regulate the ...
Cell & Microbiology
Aug 2, 2013
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A mutant protein responsible for Hutchinson-Gilford Progeria syndrome (HGPS) bars large proteins from entering the nucleus, according to a study in The Journal of Cell Biology.
Cell & Microbiology
May 6, 2013
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The notion that each gene can only codify for a single protein has been challenged for some years. Yet, the functional outcomes that may result from genes encoding more than one protein are still largely unknown.
Biotechnology
Mar 22, 2013
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(Phys.org)—While studying a mutant strain of yeast, Purdue University researchers may have found a new target for drugs to combat cholesterol and fungal diseases.
Biochemistry
Feb 25, 2013
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Rice (Oryza sativa) is an important dietary source of cadmium and can accumulate very high levels of manganese without toxic effects. However so far there has been little understanding of the uptake and transport mechanisms ...
Biotechnology
Sep 21, 2012
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1
The first step in gene expression is the exact copying of a segment of DNA by the enzyme known as RNA polymerase II, or pol II, into a mirror image RNA. Scientists recognize that pol II does not transcribe RNA via a smooth ...
Biotechnology
Aug 22, 2012
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Transcription is a cellular process by which genetic information from DNA is copied to messenger RNA for protein production. But anticancer drugs and environmental chemicals can sometimes interrupt this flow of genetic information ...
Biochemistry
Aug 21, 2012
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In an advance that could be used in masks to protect against nerve gas, scientists are reporting development of proteins that are up to 15,000 times more effective than their natural counterpart in destroying chemical warfare ...
Biochemistry
Aug 8, 2012
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Lying around in the sun all day is hazardous not just for humans but also for plants, which have no means of escape. Ultraviolet (UV) radiation from the sun can damage proteins and DNA inside cells, leading to poor growth ...
Plants & Animals
Feb 9, 2012
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