News tagged with mutant protein

Ultraviolet protection molecule in plants yields its secrets

Lying around in the sun all day is hazardous not just for humans but also for plants, which have no means of escape. Ultraviolet (UV) radiation from the sun can damage proteins and DNA inside cells, leading ...

Biology / Plants & Animals

created Feb 09, 2012 | popularity 5 / 5 (6) | comments 0 | with audio podcast

Neutrons provide first sub-nanoscale snapshots of Huntington's disease protein

Researchers at the Department of Energy's Oak Ridge National Laboratory and the University of Tennessee have for the first time successfully characterized the earliest structural formation of the disease type ...

Physics / General Physics

created May 18, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Mutant prions help cells foil harmful protein misfolding

Romping clumps of misfolded proteins are prime suspects in many neurological disorders including Alzheimer's, Parkinson's, and Creutzfeld-Jakob Disease. Those diseases are devastating and incurable, but a team of biologists ...

Biology / Cell & Microbiology

created Mar 20, 2011 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Study traces possible role of damaged DNA in tumor development

DNA provides the instruction manual for all life forms. Occasionally, instructions are not carried out properly, and bad messages are sent leading to the creation of mutant proteins and possible tumor development.

Medicine & Health / Cancer

created Mar 04, 2011 | popularity not rated yet | comments 0 | with audio podcast

HIV pays a price for invisibility

Mutations that help HIV hide from the immune system undermine the virus's ability to replicate, show an international team of researchers in the April 13 issue of the Journal of Experimental Medicine. The study was publis ...

Medicine & Health / HIV & AIDS

created Apr 13, 2009 | popularity 3.7 / 5 (3) | comments 1

Most common brain cancer may originate in neural stem cells

University of Michigan scientists have found that a deficiency in a key tumor suppressor gene in the brain leads to the most common type of adult brain cancer. The study, conducted in mice that mimic human cancer, points ...

Medicine & Health / Cancer

created Jun 01, 2009 | popularity 5 / 5 (1) | comments 0

Secretions of the mind

A molecule called calcium-dependent activator protein for secretion 2 (CAPS2) promotes the secretion of a neurotrophic factor that is critical for the proper development and survival of networks of interneurons ...

Medicine & Health / Medical research

created Feb 25, 2011 | popularity 5 / 5 (1) | comments 1

Huntington's disease protein has broader effects on brain, study shows

In Huntington's disease, the mutant protein known as huntingtin leads to the degeneration of a part of the brain known as the basal ganglia, causing the motor disturbances that represent one of the most defining features ...

Medicine & Health / Medical research

created Apr 05, 2011 | popularity not rated yet | comments 0

'Smart drug' targets new mutation, dramatically shrinks aggressive sarcoma and lung cancer

A new oral drug caused dramatic shrinkage of a patient's rare, aggressive form of soft-tissue cancer that was driven by an abnormally activated protein, physician-scientists from Dana-Farber Cancer Institute report in the ...

Medicine & Health / Cancer

created Oct 27, 2010 | popularity 5 / 5 (1) | comments 0

When it comes to sleep research, fruit flies and people make unlikely bedfellows

You may never hear fruit flies snore, but rest assured that when you're asleep they are too. According to research published in the January 2009 issue of the journal Genetics, scientists from the University of Missouri-Kansas City h ...

Biology /

created Jan 13, 2009 | popularity not rated yet | comments 0

Neuron-damaging mechanism discovered in mouse model of inherited amyotrophic lateral sclerosis

New research uncovers what may be a primary neuron-damaging insult that occurs in an inherited form of a devastating neurodegenerative disorder. The study, published by Cell Press in the August 26th issue of the journal Neuron, descri ...

Medicine & Health / Medical research

created Aug 25, 2010 | popularity 5 / 5 (2) | comments 0

Defective protein is a double hit for ataxia

The neurodegenerative disease spinocerebellar ataxia type 5 (SCA5) damages nerve cells in two ways. University of Minnesota researchers now report that the defective protein responsible for the disease cuts ...

Medicine & Health / Medical research

created Apr 05, 2010 | popularity 5 / 5 (1) | comments 0

Researchers find new method of fixing broken proteins to treat genetic diseases

Researchers at Fox Chase Cancer Center have demonstrated how it could be possible to treat genetic diseases by enhancing the natural ability of cells to restore their own mutant proteins. In particular, they found that drugs ...

Medicine & Health / Genetics

created Jan 15, 2010 | popularity 4.7 / 5 (3) | comments 0

Mutant gene's true effect revealed - giving new therapy hope

(PhysOrg.com) -- Scientists have revealed how a mutant gene that causes a connective tissue disease resulting in dwarfism does so by significantly affecting the inside of cells - opening up new therapy strategies that involve ...

Medicine & Health / Genetics

created Oct 19, 2009 | popularity not rated yet | comments 0

Huntington's disease discovery provides new hope for treatment

Australian scientists have identified the behaviour of the mutant protein 'huntingtin' which leads to the fatal Huntington's disease providing potential targets to treat the disease, a University of Melbourne study reveals.

Chemistry / Biochemistry

created Jul 28, 2010 | popularity 5 / 5 (1) | comments 0