News tagged with muscular dystrophy

Muscular dystrophy mystery solved; scientists move closer to MD solution

Muscular dystrophy, which affects approximately 250,000 people in the United States, occurs when damaged muscle tissue is replaced with fibrous, bony or fatty tissue and loses function. While scientists have identified one ...

Medicine & Health / Diseases, Conditions, Syndromes

created Feb 26, 2009 | popularity 4.9 / 5 (8) | comments 0

Scientists develop new way to grow adult stem cells in culture

Researchers at the Stanford University School of Medicine have developed a technique they believe will help scientists overcome a major hurdle to the use of adult stem cells for treating muscular dystrophy and other muscle-wasting ...

Biology / Cell & Microbiology

created Jul 15, 2010 | popularity 5 / 5 (6) | comments 0 | with audio podcast

How muscle develops: A dance of cellular skeletons

Revealing another part of the story of muscle development, Johns Hopkins researchers have shown how the cytoskeleton from one muscle cell builds finger-like projections that invade into another muscle cell's territory, eventually ...

Biology / Cell & Microbiology

created Jun 04, 2011 | popularity 4.3 / 5 (6) | comments 0 | with audio podcast

Living longer and happier

A new study from the University of Missouri may shed light on how to increase the level and quality of activity in the elderly. In the study, published in this week's edition of Public Library of Science - ONE, MU resear ...

Medicine & Health / Medical research

created Aug 19, 2009 | popularity 5 / 5 (5) | comments 2

Need muscle for a tough spot? Turn to fat stem cells

(PhysOrg.com) -- Stem cells derived from fat have a surprising trick up their sleeves: Encouraged to develop on a stiff surface, they undergo a remarkable transformation toward becoming mature muscle cells. ...

Biology / Biotechnology

created Jan 27, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Genetic source of muscular dystrophy neutralized

(PhysOrg.com) -- Researchers at the University of Rochester Medical Center have found a way to block the genetic flaw at the heart of a common form of muscular dystrophy. The results of the study, which were ...

Medicine & Health / Genetics

created Jul 16, 2009 | popularity 5 / 5 (4) | comments 0

Scientists create potent molecules aimed at treating muscular dystrophy

While RNA is an appealing drug target, small molecules that can actually affect its function have rarely been found. But now scientists from the Florida campus of The Scripps Research Institute have for the first time designed ...

Chemistry / Biochemistry

created Feb 22, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Researchers develop new muscular dystrophy treatment approach using human stem cells

Researchers from the University of Minnesota's Lillehei Heart Institute have effectively treated muscular dystrophy in mice using human stem cells derived from a new process that – for the first time – makes the ...

Biology / Cell & Microbiology

created May 04, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

New perspective in ion channel indicates treatment potential

Scientists researching a toxin extracted from the venom of the honey bee have used this to inform the design of new treatments to alleviate the symptoms of conditions such as muscular dystrophy, depression ...

Chemistry / Biochemistry

created Jul 09, 2010 | popularity 4.5 / 5 (4) | comments 0 | with audio podcast

Investigating muscle repair, scientists follow their noses

When muscle cells need repair, they use odor-detecting tools found in the nose to start the process, researchers have discovered.

Biology / Cell & Microbiology

created Nov 16, 2009 | popularity 4 / 5 (4) | comments 0

Study reveals intermediary steps of genetic encoding for the first time

In a new study this week in Nature, researchers at Brandeis University and the MRC Laboratory of Molecular Biology (Cambridge, U.K.) for the first time shed light on a crucial step in the complex process by which human geneti ...

Medicine & Health / Genetics

created Mar 27, 2009 | popularity 5 / 5 (3) | comments 0

Gene therapy for muscular dystrophy shows promise beyond safety

Researchers have cleared a safety hurdle in efforts to develop a gene therapy for a form of muscular dystrophy that disables patients by gradually weakening muscles near the hips and shoulders.

Medicine & Health / Neuroscience

created Apr 15, 2009 | popularity 5 / 5 (3) | comments 0

Chemists Rationally Design Inhibitors Against an RNA Molecule that Causes Myotonic Muscular Dystrophy

(PhysOrg.com) -- Chemists at the University at Buffalo have used rational drug design to synthesize small, cell-permeable molecules that are effective in vitro against two common types of myotonic muscular ...

Chemistry / Biochemistry

created Aug 07, 2009 | popularity 5 / 5 (3) | comments 0

Uncovering the cause of a common form of muscular dystrophy

An international team of researchers led by an investigator from Fred Hutchinson Cancer Research Center has made a second critical advance in determining the cause of a common form of muscular dystrophy known as facioscapulohumeral ...

Medicine & Health / Genetics

created Oct 28, 2010 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Human protein improves muscle function of muscular dystrophy mice

A novel potential therapy based on a natural human protein significantly slows muscle damage and improves function in mice who have the same genetic mutation as boys with the most common form of muscular dystrophy, according ...

Medicine & Health / Medical research

created Dec 27, 2010 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast

Muscular dystrophy

Muscular dystrophy (abbreviated MD) refers to a group of genetic, hereditary muscle diseases that weaken the muscles that move the human body. Muscular dystrophies are characterized by progressive skeletal muscle weakness, defects in muscle proteins, and the death of muscle cells and tissue. Nine diseases including Duchenne, Becker, limb girdle, congenital, facioscapulohumeral, myotonic, oculopharyngeal, distal, and Emery-Dreifuss are always classified as muscular dystrophy but there are more than 100 diseases in total with similarities to muscular dystrophy. Most types of MD are multi-system disorders with manifestations in body systems including the heart, gastrointestinal and nervous systems, endocrine glands, skin, eyes and other organs.

In the 1860s, descriptions of boys who grew progressively weaker, lost the ability to walk, and died at an early age became more prominent in medical journals. In the following decade, French neurologist Guillaume Duchenne gave a comprehensive account of 13 boys with the most common and severe form of the disease (which now carries his name — Duchenne muscular dystrophy). It soon became evident that the disease had more than one form, and that these diseases affected males of all ages.[citation needed]

For more information about Muscular dystrophy, read the full article at Wikipedia.
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