News tagged with muscular dystrophy

Researchers develop new muscular dystrophy treatment approach using human stem cells

Researchers from the University of Minnesota's Lillehei Heart Institute have effectively treated muscular dystrophy in mice using human stem cells derived from a new process that – for the first time – makes the ...

Biology / Cell & Microbiology

created May 04, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Scientists create potent molecules aimed at treating muscular dystrophy

While RNA is an appealing drug target, small molecules that can actually affect its function have rarely been found. But now scientists from the Florida campus of The Scripps Research Institute have for the first time designed ...

Chemistry / Biochemistry

created Feb 22, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Need muscle for a tough spot? Turn to fat stem cells

(PhysOrg.com) -- Stem cells derived from fat have a surprising trick up their sleeves: Encouraged to develop on a stiff surface, they undergo a remarkable transformation toward becoming mature muscle cells. ...

Biology / Biotechnology

created Jan 27, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Scientists develop new way to grow adult stem cells in culture

Researchers at the Stanford University School of Medicine have developed a technique they believe will help scientists overcome a major hurdle to the use of adult stem cells for treating muscular dystrophy and other muscle-wasting ...

Biology / Cell & Microbiology

created Jul 15, 2010 | popularity 5 / 5 (6) | comments 0 | with audio podcast

How muscle develops: A dance of cellular skeletons

Revealing another part of the story of muscle development, Johns Hopkins researchers have shown how the cytoskeleton from one muscle cell builds finger-like projections that invade into another muscle cell's territory, eventually ...

Biology / Cell & Microbiology

created Jun 04, 2011 | popularity 4.3 / 5 (6) | comments 0 | with audio podcast

Scientists identify gene that could hold the key to muscle repair

(PhysOrg.com) -- Researchers have long questioned why patients with Duchenne muscular dystrophy (DMD) tend to manage well through childhood and adolescence, yet succumb to their disease in early adulthood, or why elderly ...

Medicine & Health / Genetics

created Apr 18, 2011 | popularity not rated yet | comments 0 | with audio podcast

Uncovering the cause of a common form of muscular dystrophy

An international team of researchers led by an investigator from Fred Hutchinson Cancer Research Center has made a second critical advance in determining the cause of a common form of muscular dystrophy known as facioscapulohumeral ...

Medicine & Health / Genetics

created Oct 28, 2010 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Human protein improves muscle function of muscular dystrophy mice

A novel potential therapy based on a natural human protein significantly slows muscle damage and improves function in mice who have the same genetic mutation as boys with the most common form of muscular dystrophy, according ...

Medicine & Health / Medical research

created Dec 27, 2010 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast

Living longer and happier

A new study from the University of Missouri may shed light on how to increase the level and quality of activity in the elderly. In the study, published in this week's edition of Public Library of Science - ONE, MU resear ...

Medicine & Health / Medical research

created Aug 19, 2009 | popularity 5 / 5 (5) | comments 2

Scientists pinpoint earliest steps of common form of muscular dystrophy

Nearly two decades after they identified the specific genetic flaw that causes a common type of muscular dystrophy, scientists believe they have figured out how that flaw brings about the disease. The finding by an international ...

Medicine & Health / Genetics

created Aug 19, 2010 | popularity not rated yet | comments 0 | with audio podcast

Electric field propels worms to test new drugs

A Nobel-winning process for testing new drugs to treat diseases such as Huntington's, Parkinson's, and muscular dystrophy is getting an electrical charge.

Chemistry / Biochemistry

created Jan 05, 2010 | popularity not rated yet | comments 0 | with audio podcast

Caught on tape: Muscle stem cells captured on video

When muscle tissue experiences trauma or disease, such as muscular dystrophy, stem cells in the muscle known as "satellite cells" respond to repair and regenerate the muscle. These cells are particularly important in neuromuscular ...

Medicine & Health / Medical research

created May 06, 2010 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Duchenne muscular dystrophy is ultimately a stem cell disease

For years, scientists have tried to understand why children with Duchenne muscular dystrophy experience severe muscle wasting and eventual death. After all, laboratory mice with the same mutation that causes the disease in ...

Medicine & Health / Medical research

created Dec 09, 2010 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Chemists Rationally Design Inhibitors Against an RNA Molecule that Causes Myotonic Muscular Dystrophy

(PhysOrg.com) -- Chemists at the University at Buffalo have used rational drug design to synthesize small, cell-permeable molecules that are effective in vitro against two common types of myotonic muscular ...

Chemistry / Biochemistry

created Aug 07, 2009 | popularity 5 / 5 (3) | comments 0

New perspective in ion channel indicates treatment potential

Scientists researching a toxin extracted from the venom of the honey bee have used this to inform the design of new treatments to alleviate the symptoms of conditions such as muscular dystrophy, depression ...

Chemistry / Biochemistry

created Jul 09, 2010 | popularity 4.5 / 5 (4) | comments 0 | with audio podcast

Muscular dystrophy

Muscular dystrophy (abbreviated MD) refers to a group of genetic, hereditary muscle diseases that weaken the muscles that move the human body. Muscular dystrophies are characterized by progressive skeletal muscle weakness, defects in muscle proteins, and the death of muscle cells and tissue. Nine diseases including Duchenne, Becker, limb girdle, congenital, facioscapulohumeral, myotonic, oculopharyngeal, distal, and Emery-Dreifuss are always classified as muscular dystrophy but there are more than 100 diseases in total with similarities to muscular dystrophy. Most types of MD are multi-system disorders with manifestations in body systems including the heart, gastrointestinal and nervous systems, endocrine glands, skin, eyes and other organs.

In the 1860s, descriptions of boys who grew progressively weaker, lost the ability to walk, and died at an early age became more prominent in medical journals. In the following decade, French neurologist Guillaume Duchenne gave a comprehensive account of 13 boys with the most common and severe form of the disease (which now carries his name — Duchenne muscular dystrophy). It soon became evident that the disease had more than one form, and that these diseases affected males of all ages.[citation needed]

For more information about Muscular dystrophy, read the full article at Wikipedia.
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