News tagged with muscular dystrophy
Researchers develop new muscular dystrophy treatment approach using human stem cells
Researchers from the University of Minnesota's Lillehei Heart Institute have effectively treated muscular dystrophy in mice using human stem cells derived from a new process that for the first time makes the ...
May 04, 2012 |
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Scientists create potent molecules aimed at treating muscular dystrophy
While RNA is an appealing drug target, small molecules that can actually affect its function have rarely been found. But now scientists from the Florida campus of The Scripps Research Institute have for the first time designed ...
Feb 22, 2012 |
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Need muscle for a tough spot? Turn to fat stem cells
(PhysOrg.com) -- Stem cells derived from fat have a surprising trick up their sleeves: Encouraged to develop on a stiff surface, they undergo a remarkable transformation toward becoming mature muscle cells. ...
Jan 27, 2012 |
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How muscle develops: A dance of cellular skeletons
Revealing another part of the story of muscle development, Johns Hopkins researchers have shown how the cytoskeleton from one muscle cell builds finger-like projections that invade into another muscle cell's territory, eventually ...
Jun 04, 2011 |
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Scientists identify gene that could hold the key to muscle repair
(PhysOrg.com) -- Researchers have long questioned why patients with Duchenne muscular dystrophy (DMD) tend to manage well through childhood and adolescence, yet succumb to their disease in early adulthood, or why elderly ...
Apr 18, 2011 |
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Researchers identify new form of muscular dystrophy
A strong international collaboration and a single patient with mild muscle disease and severe cognitive impairment have allowed University of Iowa researchers to identify a new gene mutation that causes muscular dystrophy.
Medicine & Health / Medical research
Mar 09, 2011 |
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Using stem cells to regrow muscle, bone
Among the most debilitating of diseases are degenerative ones, in which a persons health slowly declines over time. And some of the worst of these diseases involve the deterioration of muscle or bone.
Medicine & Health / Medical research
Mar 09, 2011 |
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Human protein improves muscle function of muscular dystrophy mice
A novel potential therapy based on a natural human protein significantly slows muscle damage and improves function in mice who have the same genetic mutation as boys with the most common form of muscular dystrophy, according ...
Medicine & Health / Medical research
Dec 27, 2010 |
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Duchenne muscular dystrophy is ultimately a stem cell disease
For years, scientists have tried to understand why children with Duchenne muscular dystrophy experience severe muscle wasting and eventual death. After all, laboratory mice with the same mutation that causes the disease in ...
Medicine & Health / Medical research
Dec 09, 2010 |
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Rare genetic disorder highlights importance of selenium
A rare genetic disorder has highlighted the importance to human health of selenium, a little known trace element. The discovery, reported today in the Journal of Clinical Investigation, may also shed light ...
Medicine & Health / Medical research
Nov 16, 2010 |
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Uncovering the cause of a common form of muscular dystrophy
An international team of researchers led by an investigator from Fred Hutchinson Cancer Research Center has made a second critical advance in determining the cause of a common form of muscular dystrophy known as facioscapulohumeral ...
Oct 28, 2010 |
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First clinical trial of gene therapy for muscular dystrophy lends insight into the disease
A clinical trial designed to replace the genetic defect causing the most common form of muscular dystrophy has uncovered an unexpected aspect of the disease. The trial, based on therapy designed by scientists at the University ...
Medicine & Health / Medical research
Oct 06, 2010 |
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Blacks with muscular dystrophy die 10-12 years younger than whites: study
African Americans with muscular dystrophy die 10 to 12 years younger than their white counterparts, according to research published in the Sept. 14 issue of Neurology, the medical journal of the American Academy of Neurol ...
Sep 13, 2010 |
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International effort to improve muscular dystrophy treatment
A large international study aimed at improving the care of muscular dystrophy patients worldwide is being launched by physicians, physical therapists, and researchers at the University of Rochester Medical Center.
Medicine & Health / Diseases, Conditions, Syndromes
Sep 03, 2010 |
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Scientists pinpoint earliest steps of common form of muscular dystrophy
Nearly two decades after they identified the specific genetic flaw that causes a common type of muscular dystrophy, scientists believe they have figured out how that flaw brings about the disease. The finding by an international ...
Aug 19, 2010 |
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Muscular dystrophy
Muscular dystrophy (abbreviated MD) refers to a group of genetic, hereditary muscle diseases that weaken the muscles that move the human body. Muscular dystrophies are characterized by progressive skeletal muscle weakness, defects in muscle proteins, and the death of muscle cells and tissue. Nine diseases including Duchenne, Becker, limb girdle, congenital, facioscapulohumeral, myotonic, oculopharyngeal, distal, and Emery-Dreifuss are always classified as muscular dystrophy but there are more than 100 diseases in total with similarities to muscular dystrophy. Most types of MD are multi-system disorders with manifestations in body systems including the heart, gastrointestinal and nervous systems, endocrine glands, skin, eyes and other organs.
In the 1860s, descriptions of boys who grew progressively weaker, lost the ability to walk, and died at an early age became more prominent in medical journals. In the following decade, French neurologist Guillaume Duchenne gave a comprehensive account of 13 boys with the most common and severe form of the disease (which now carries his name — Duchenne muscular dystrophy). It soon became evident that the disease had more than one form, and that these diseases affected males of all ages.[citation needed]
For more information about Muscular dystrophy, read the full article at
Wikipedia.
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