News tagged with muscular dystrophy

Researchers develop new muscular dystrophy treatment approach using human stem cells

Researchers from the University of Minnesota's Lillehei Heart Institute have effectively treated muscular dystrophy in mice using human stem cells derived from a new process that – for the first time – makes the ...

Biology / Cell & Microbiology

created May 04, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Scientists create potent molecules aimed at treating muscular dystrophy

While RNA is an appealing drug target, small molecules that can actually affect its function have rarely been found. But now scientists from the Florida campus of The Scripps Research Institute have for the first time designed ...

Chemistry / Biochemistry

created Feb 22, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Need muscle for a tough spot? Turn to fat stem cells

(PhysOrg.com) -- Stem cells derived from fat have a surprising trick up their sleeves: Encouraged to develop on a stiff surface, they undergo a remarkable transformation toward becoming mature muscle cells. ...

Biology / Biotechnology

created Jan 27, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

How muscle develops: A dance of cellular skeletons

Revealing another part of the story of muscle development, Johns Hopkins researchers have shown how the cytoskeleton from one muscle cell builds finger-like projections that invade into another muscle cell's territory, eventually ...

Biology / Cell & Microbiology

created Jun 04, 2011 | popularity 4.3 / 5 (6) | comments 0 | with audio podcast

Scientists identify gene that could hold the key to muscle repair

(PhysOrg.com) -- Researchers have long questioned why patients with Duchenne muscular dystrophy (DMD) tend to manage well through childhood and adolescence, yet succumb to their disease in early adulthood, or why elderly ...

Medicine & Health / Genetics

created Apr 18, 2011 | popularity not rated yet | comments 0 | with audio podcast

Researchers identify new form of muscular dystrophy

A strong international collaboration and a single patient with mild muscle disease and severe cognitive impairment have allowed University of Iowa researchers to identify a new gene mutation that causes muscular dystrophy.

Medicine & Health / Medical research

created Mar 09, 2011 | popularity 5 / 5 (2) | comments 0

Using stem cells to regrow muscle, bone

Among the most debilitating of diseases are degenerative ones, in which a person’s health slowly declines over time. And some of the worst of these diseases involve the deterioration of muscle or bone.

Medicine & Health / Medical research

created Mar 09, 2011 | popularity not rated yet | comments 0

Human protein improves muscle function of muscular dystrophy mice

A novel potential therapy based on a natural human protein significantly slows muscle damage and improves function in mice who have the same genetic mutation as boys with the most common form of muscular dystrophy, according ...

Medicine & Health / Medical research

created Dec 27, 2010 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast

Duchenne muscular dystrophy is ultimately a stem cell disease

For years, scientists have tried to understand why children with Duchenne muscular dystrophy experience severe muscle wasting and eventual death. After all, laboratory mice with the same mutation that causes the disease in ...

Medicine & Health / Medical research

created Dec 09, 2010 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Rare genetic disorder highlights importance of selenium

A rare genetic disorder has highlighted the importance to human health of selenium, a little known trace element. The discovery, reported today in the Journal of Clinical Investigation, may also shed light ...

Medicine & Health / Medical research

created Nov 16, 2010 | popularity 5 / 5 (1) | comments 1

Uncovering the cause of a common form of muscular dystrophy

An international team of researchers led by an investigator from Fred Hutchinson Cancer Research Center has made a second critical advance in determining the cause of a common form of muscular dystrophy known as facioscapulohumeral ...

Medicine & Health / Genetics

created Oct 28, 2010 | popularity 5 / 5 (3) | comments 0 | with audio podcast

First clinical trial of gene therapy for muscular dystrophy lends insight into the disease

A clinical trial designed to replace the genetic defect causing the most common form of muscular dystrophy has uncovered an unexpected aspect of the disease. The trial, based on therapy designed by scientists at the University ...

Medicine & Health / Medical research

created Oct 06, 2010 | popularity 5 / 5 (1) | comments 0

Blacks with muscular dystrophy die 10-12 years younger than whites: study

African Americans with muscular dystrophy die 10 to 12 years younger than their white counterparts, according to research published in the Sept. 14 issue of Neurology, the medical journal of the American Academy of Neurol ...

Medicine & Health / Health

created Sep 13, 2010 | popularity not rated yet | comments 0

International effort to improve muscular dystrophy treatment

A large international study aimed at improving the care of muscular dystrophy patients worldwide is being launched by physicians, physical therapists, and researchers at the University of Rochester Medical Center.

Medicine & Health / Diseases, Conditions, Syndromes

created Sep 03, 2010 | popularity not rated yet | comments 1

Scientists pinpoint earliest steps of common form of muscular dystrophy

Nearly two decades after they identified the specific genetic flaw that causes a common type of muscular dystrophy, scientists believe they have figured out how that flaw brings about the disease. The finding by an international ...

Medicine & Health / Genetics

created Aug 19, 2010 | popularity not rated yet | comments 0 | with audio podcast

Muscular dystrophy

Muscular dystrophy (abbreviated MD) refers to a group of genetic, hereditary muscle diseases that weaken the muscles that move the human body. Muscular dystrophies are characterized by progressive skeletal muscle weakness, defects in muscle proteins, and the death of muscle cells and tissue. Nine diseases including Duchenne, Becker, limb girdle, congenital, facioscapulohumeral, myotonic, oculopharyngeal, distal, and Emery-Dreifuss are always classified as muscular dystrophy but there are more than 100 diseases in total with similarities to muscular dystrophy. Most types of MD are multi-system disorders with manifestations in body systems including the heart, gastrointestinal and nervous systems, endocrine glands, skin, eyes and other organs.

In the 1860s, descriptions of boys who grew progressively weaker, lost the ability to walk, and died at an early age became more prominent in medical journals. In the following decade, French neurologist Guillaume Duchenne gave a comprehensive account of 13 boys with the most common and severe form of the disease (which now carries his name — Duchenne muscular dystrophy). It soon became evident that the disease had more than one form, and that these diseases affected males of all ages.[citation needed]

For more information about Muscular dystrophy, read the full article at Wikipedia.
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