News tagged with multiple myeloma
New class of drugs for the reversible inhibition of proteasomes
As the "recycling plant" of the cell, the proteasome regulates vitally important functions. When it is inhibited, the cell chokes on its own waste. Cancer cells, in particular, are very sensitive because they ...
Nov 22, 2011 |
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Researchers sequence multiple myeloma genome in landmark study
Using new genome sequencing technologies, researchers from the John Theurer Cancer Center at Hackensack University Medical Center joined colleagues from 20 major North American research institutions to publish the first complete ...
Mar 23, 2011 |
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Research first to combine targeted agents to kill multiple myeloma cells
(PhysOrg.com) -- Scientists at Virginia Commonwealth University Massey Cancer Center have developed a novel treatment strategy for multiple myeloma that pairs two targeted agents to kill cancer cells. The study’s findings, ...
Feb 10, 2011 |
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Researchers pinpoint how one cancer gene functions
For several decades, researchers have been linking genetic mutations to diseases ranging from cancer to developmental abnormalities. What hasn't been clear, however, is how the body's genome sustains such destructive glitches ...
Feb 02, 2011 |
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Potential new multiple myeloma therapy developed
A treatment for the incurable blood cancer Multiple Myeloma could be developed in the future if a groundbreaking scientific discovery is applied to new Leeds-based research into the disease.
Jan 06, 2011 |
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Protein offers new clue to cause and treatment for kidney disease
University of Alabama at Birmingham researchers have pinpointed a protein that compromises the kidney's filtering ability, causing nephrotic syndrome, and demonstrated that a naturally occurring precursor of an acid in the ...
Medicine & Health / Medical research
Dec 12, 2010 |
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Drug combination shows promise for newly diagnosed blood cancer patients, study finds
A new three-drug combination used to treat the blood cancer multiple myeloma may be effective as a front-line therapy for newly diagnosed patients, according to a study led by the University of Michigan Comprehensive Cancer ...
Dec 09, 2010 |
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A decade of refinements in transplantation improves long-term survival of blood cancers
A decade of refinements in marrow and stem cell transplantation to treat blood cancers significantly reduced the risk of treatment-related complications and death, according to an institutional self-analysis of transplant-patient ...
Nov 24, 2010 |
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Study finds bortezomib to be promising treatment for rheumatoid arthritis
A new study by Greek researchers suggests that the biologic drug bortezomib (Velcade), a proteasome inhibitor used to treat multiple myeloma (bone marrow cancer), may represent a promising treatment for rheumatoid arthritis ...
Medicine & Health / Diseases, Conditions, Syndromes
Nov 03, 2010 |
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Blood might carry an untapped source of biomarkers
Researchers have uncovered a potential source of blood-derived biomarkers for certain kinds of cancer, according to a study.
Medicine & Health / Medical research
Nov 02, 2010 |
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Study identifies key molecules in multiple myeloma
New research links three molecules to a critical tumor suppressor gene that is often turned off in multiple myeloma, a presently incurable cancer of the blood.
Oct 26, 2010 |
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Scientists discover inner workings of potent cancer drug
A potent drug derived from an evergreen tree may soon save the lives of some patients with the deadliest form of breast cancer. According to the National Cancer Institute, breast cancer will claim approximately ...
Oct 14, 2010 |
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High response rates seen in phase-III trial of chemotherapy, new drug and stem cells in myeloma
The first study of its kind comparing two different approaches to treating newly diagnosed multiple myeloma has found that both treatments achieved a positive response, researchers said at the 35th Congress of the European ...
Oct 12, 2010 |
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Surgical technique relieves painful spine fractures in patients with metastatic cancer
A surgical technique appears to offer quick and effective relief for debilitating spinal fractures often suffered by patients with metastatic cancer, researchers reported at the 35th Congress of the European Society for Medical ...
Oct 09, 2010 |
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$93,000 cancer drug: How much is a life worth?
Cancer patients, brace yourselves. Many new drug treatments cost nearly $100,000 a year, sparking fresh debate about how much a few months more of life is worth.
Sep 26, 2010 |
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Multiple myeloma
Multiple myeloma (from myelo-, bone marrow), also known as MM, myeloma, plasma cell myeloma, or as Kahler's disease (after Otto Kahler) is a cancer of the white blood cells known as plasma cells, which produce antibodies.
These plasma cells, or B cells, are part of the immune system, formed in bone marrow, and numerous in lymphatics. Myeloma is incurable, but remissions may be induced with steroids, chemotherapy, thalidomide and stem cell transplants.
There were 15,270 cases diagnosed and 11,070 deaths in the United States in 2004, and an incidence of 4/100,000 worldwide. Median survival is 50–55 months. Chromosome diagnosis can separate patients into more or less favorable prognoses.
Myeloma is part of the broad group of diseases called hematological malignancies.
For more information about Multiple myeloma, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
