News tagged with mrna
Researchers solve structure of human protein critical for silencing genes
In a study published in the journal Cell on May 24, Cold Spring Harbor Laboratory (CSHL) scientists describe the three-dimensional atomic structure of a human protein bound to a piece of RNA that "guides" the pr ...
May 25, 2012 |
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Researchers reveal an RNA modification influences thousands of genes
Over the past decade, research in the field of epigenetics has revealed that chemically modified bases are abundant components of the human genome and has forced us to abandon the notion we've had since high school genetics ...
May 17, 2012 |
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Genes ex silico: Computer-designed virus yields phenotype expression benefits
(PhysOrg.com) -- Gene therapy is medicine’s rising star with adeno-associated virus (AAV) vectors – nonpathogenic parvoviruses – among the most promising supporting actors, due largely to their ...
Aug 29, 2011 |
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Biomolecular computer can autonomously sense multiple signs of disease
(PhysOrg.com) -- In the future, nano-sized computers implanted in the human body could autonomously scan for disease indicators, diagnose diseases, and control the release of the appropriate drugs. Although ...
Nanotechnology / Bio & Medicine
Jul 06, 2011 |
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Scientists observe single gene activity in living cells
Researchers at Albert Einstein College of Medicine of Yeshiva University have for the first time observed the activity of a single gene in living cells. In an unprecedented study, published in the April 22 online edition ...
Apr 21, 2011 |
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Scientists find the structure of a key 'gene silencer' protein
Scientists at The Scripps Research Institute have determined the three-dimensional atomic structure of a human protein that is centrally involved in regulating the activities of cells. Knowing the precise ...
Apr 26, 2012 |
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Controlling self-renewal of stem cells
(PhysOrg.com) -- Scientists from the Friedrich Miescher Institute for Biomedical Research (FMI) are the first to establish a direct link between a conserved stem cell factor and the cell cycle regulation in ...
Sep 02, 2011 |
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Built-in 'self-destruct timer' causes ultimate death of messenger RNA in cells
Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered the first known mechanism by which cells control the survival of messenger RNA (mRNA) -- arguably biology's most important molecule. ...
Dec 22, 2011 |
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Tiny LNA-based compounds inhibit entire disease-associated microRNA families
A study published online in this week's Nature Genetics demonstrates that tiny Locked Nucleic Acid (LNA)-based compounds developed by Santaris Pharma A/S can inhibit entire disease-associated microRNA families. This provid ...
Mar 20, 2011 |
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A lack of structure facilitates protein synthesis
Having an easily accessible starting point on messenger RNA increases protein formation, scientists from the Max Planck Institute of Molecular Plant Physiology in Potsdam have discovered.
Jun 28, 2011 |
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New mechanism in the regulation of human genes
Scientists at the Technical University of Munich and the Helmholtz Zentrum Muenchen and along with their colleagues from the European Molecular Biology Laboratory (EMBL) in Heidelberg and the Centre for Genomic Regulation ...
Jul 14, 2011 |
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Researchers achieve major breakthrough in cell reprogramming
(PhysOrg.com) -- A group of Harvard Stem Cell Institute (HSCI) researchers has made so significant a leap forward in reprogramming human adult cells that HSCI co-director Doug Melton, who did not participate in the work, ...
Sep 30, 2010 |
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Nature's quality control in yeast
(PhysOrg.com) -- Scientists know that in yeast cells, as in other cells, it’s the job of ribosomes to make proteins out of amino acids using information coded in the messenger RNA (mRNA).
Aug 30, 2010 |
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Researchers uncover new mechanistic insight into mRNA biogenesis and export
A team of EU-funded Spanish and Polish researchers have revealed the structure of a protein complex that is essential for messenger RNA (mRNA) biogenesis and export. Writing in the European Molecular Biology ...
Mar 19, 2012 |
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Researchers demonstrate that messenger RNA are lost in translation
Case Western Reserve University School of Medicine assistant professor in the Center for RNA Molecular Biology, Jeff Coller, Ph.D., and his team discovered that messenger RNA (mRNA) predominately degrade on ribosomes, fundamentally ...
Aug 23, 2009 |
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