News tagged with mouse genome
Study dusts sugar coating off little-known regulation in cells
In Alzheimer's disease, brain neurons become clogged with tangled proteins. Scientists suspect these tangles arise partly due to malfunctions in a little-known regulatory system within cells. Now, researchers have dramatically ...
Apr 16, 2012 |
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Mouse genetic blueprint developed
Researchers have developed a valuable mouse genetic blueprint that will accelerate future research and understanding of human genetics. The international team, led by researchers at the Wellcome Trust Sanger ...
Sep 14, 2011 |
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A knockout resource for mouse genetics
An international consortium of researchers report today in Nature that they have knocked out almost 40 per cent of the genes in the mouse genome. The completed resource will power studies of gene activity in models of hum ...
Jun 15, 2011 |
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Meet the complete mouse -- whole mouse genome sequence published
Are you a man or a mouse? A new paper, published in this week's issue of PLoS Biology, explores exactly what distinguishes our genome from that of the lab mouse. In the first comprehensive comparison betwee ...
May 27, 2009 |
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Discovery leads to rapid mouse 'personalized trials' in breast cancer
One person's breast cancer is not the same as another person's, because the gene mutations differ in each tumor. That makes it difficult to match the best therapy with the individual patient.
Sep 04, 2009 |
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Study pinpoints novel cancer gene and biomarker
(PhysOrg.com) -- Dana-Farber Cancer Institute scientists' discovery of a cancer-causing gene - the first in its family to be linked to cancer - demonstrates how the panoramic view of genomics and the close-up ...
Jun 24, 2009 |
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Mouse cancer genome unveils genetic errors in human cancers
Scientists who pioneered sequencing the genomes of cancer patients to find novel genetic changes at the root of the disease now have turned their attention to a laboratory workhorse -- a mouse.
Mar 23, 2011 |
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Cholera strain evolves new mechanism for causing disease
New clinical strains of cholera appear to have evolved a distinctly different mechanism to cause the same disease according to research published in the current issue of the online journal mBio.
Dec 09, 2010 |
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New reagents for genomic engineering of mouse models to understand human disease
A new study published in Disease Models and Mechanisms, reports new tools for generating specifically targeted genetic mutations in bacteria, mammalian cells and mice. The new recombinase, Dre, is similar to its predecessor, Cre, b ...
Aug 19, 2009 |
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Switching off protein 'thermostat' shuts down deadly fungal disease
(PhysOrg.com) -- University of Toronto researchers have discovered that by switching off a protein "thermostat" that controls the growth and spread of lethal fungal infections, the disease may be halted.
Mar 26, 2009 |
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