Bioengineers and life scientists incorporate hybridoma technology to produce large numbers of identical antibodies, and develop new antibody therapeutics and diagnostics. Recent preclinical and clinical studies on the technology ...
A new mathematical model describes how highly concentrated antibody solutions separate into different phases, similar to an oil and water mixture. This separation can reduce the stability and shelf-life of some drugs that ...
Materials Science
Jul 22, 2019
0
150
According to the Mayo Clinic, about 20% of breast cancers make abnormally high levels of a protein called human epidermal growth factor receptor 2 (HER2). When displayed on the surface of cancer cells, this signaling protein ...
Bio & Medicine
Jun 5, 2019
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485
According to the World Health Organization, about 100,000 people die from venomous snakebites every year. Many of these fatalities occur in rural areas of developing countries that lack access to antivenoms. That's why researchers ...
Other
Jan 30, 2019
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4
Researchers at Vanderbilt University Medical Center and colleagues have isolated a human monoclonal antibody that can "neutralize" the West Nile virus and potentially prevent a leading cause of viral encephalitis (brain inflammation) ...
Cell & Microbiology
Nov 20, 2018
1
200
Why some biopharmaceuticals have a longer shelf life than others is a problem that has baffled scientists and manufacturers alike. Even the same medication, produced by different manufacturers, can vary in its storage life.
Biochemistry
Sep 28, 2018
0
10
When the National Institute of Standards and Technology (NIST) issued the world's first standardized monoclonal antibody (mAb) in July 2016, the exhaustively analyzed protein known as NISTmAb (NIST Reference Material 8671) ...
Biotechnology
Jul 31, 2018
0
7
Clostridium difficile (C. difficile) infection is the leading cause of hospital-acquired diarrhea, causing nearly a half million infections in the United States each year. Recurrence after treatment with antibiotics is common ...
Biochemistry
Jan 26, 2018
0
10
Scientists have created a high-speed method to generate thousands of different, small, stable proteins from scratch that can be custom-designed to bind to specific therapeutic targets.
Biochemistry
Sep 27, 2017
0
331
The discovery of a chemical compound that halts the production of a small set of proteins while leaving general protein production untouched suggests a new drug search strategy: Find compounds that target undesired proteins ...
Cell & Microbiology
Mar 21, 2017
0
203
