Harnessing AI to discover new drugs inspired by nature

Artificial intelligence (AI) is able to recognize the biological activity of natural products in a targeted manner, as researchers at ETH Zurich have demonstrated. Moreover, AI helps to find molecules that have the same effect ...

Breakthrough for tracking RNA with fluorescence

Researchers at Chalmers University of Technology, Sweden, have succeeded in developing a method to label mRNA molecules, and thereby follow, in real time, their path through cells, using a microscope—without affecting their ...

Chimeric viruses unearth hidden gems in dengue virus structure

In a recent study, Australian scientists used an original approach to resolve the 3D structure of flaviviruses with an unprecedented level of detail, identifying small molecules known as 'pocket factors' as new therapeutic ...

Release of drugs from a supramolecular cage

How can a highly effective drug be transported to the precise location in the body where it is needed? In the journal Angewandte Chemie, chemists at Heinrich Heine University Düsseldorf (HHU) together with colleagues in ...

Massive fragment screen points way to new SARS-CoV-2 inhibitors

New research published in Science Advances provides a template for how to develop directly acting antivirals with novel modes of action that would combat COVID-19 by suppressing the SARS-CoV-2 viral infection. The study focused ...

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