New atom-level insight into drug-target residence time

A new study from the University of Eastern Finland and the University of Tübingen helps to explain what defines how long a drug molecule stays bound to its target.

Discovering new drugs, inspired by Darwinian theory

The body must constantly defend itself against bacteria and viruses. It generates millions of different antibodies, which are selected to recognize the enemy and trigger the best possible immune response. Scientists use these ...

High-resolution mapping method for G4 DNA structures developed

While investigating the unusual G quadruplex DNA structure (G4), the Simon Elsässer group has developed a more accurate method for mapping these structures in the genome. G4 CUT&Tag revealed numerous G4s in the human and ...

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