New atom-level insight into drug-target residence time
A new study from the University of Eastern Finland and the University of Tübingen helps to explain what defines how long a drug molecule stays bound to its target.
A new study from the University of Eastern Finland and the University of Tübingen helps to explain what defines how long a drug molecule stays bound to its target.
Molecular & Computational biology
Jan 28, 2022
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11
A European research group has developed an exciting new imaging method on Diamond Light Source's beamline B23 that could improve the characterisation of chiral molecules in pharmaceuticals and other chiral molecules in the ...
Analytical Chemistry
Jan 11, 2022
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6
The body must constantly defend itself against bacteria and viruses. It generates millions of different antibodies, which are selected to recognize the enemy and trigger the best possible immune response. Scientists use these ...
Biochemistry
Dec 6, 2021
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30
A research team at Lund University in Sweden has succeeded in producing two molecules that are otherwise only formed by microorganisms from extremely contaminated wastewater in an abandoned mine in South Korea. The method, ...
Biochemistry
Dec 6, 2021
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1552
While investigating the unusual G quadruplex DNA structure (G4), the Simon Elsässer group has developed a more accurate method for mapping these structures in the genome. G4 CUT&Tag revealed numerous G4s in the human and ...
Biotechnology
Dec 6, 2021
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52
Scientists at ETH Zurich have developed a new method to determine how proteins are organized on the surface of cells. Insights gained with the technology could lead to the development of novel drugs to fight cancer.
Cell & Microbiology
Dec 2, 2021
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112
An FDA-approved drug for hepatitis C can increase bacterial sensitivity to antibiotics and reduce the likelihood of antibiotic resistance, according to a new study led by New York University researchers published in Cell ...
Biochemistry
Nov 23, 2021
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97
Rearranging the parts of a molecule is like rearranging the contents of a tightly packed suitcase: You must go through a number of steps, taking objects in and out to get the configuration you want.
Biochemistry
Nov 18, 2021
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75
Chemistry researchers at the University of Bath have developed a new method using blue light to create pharmaceuticals in a more sustainable way, significantly reducing the amount of energy needed and the chemical waste created ...
Materials Science
Nov 17, 2021
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206
Scientists have known for decades that a certain class of enzymes is an important player in cell biology because they frequently mutate and become major drivers of cancer.
Biochemistry
Oct 11, 2021
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126