Immune function remodeled by mitochondrial shape

A new study focused on the immune system's Th17 cells suggests that the shape and function of their mitochondria is important in autoimmune and inflammatory disorders, such as multiple sclerosis. T helper 17 (Th17) cells ...

Small proteins play big role in cellular energy balance

Scientists at Duke-NUS Medical School have discovered new molecular details of how cells ensure that their energy supply is adjusted to meet energy demand. Their study, carried out in collaboration with researchers at the ...

First mouse model with mitochondrial tRNALeu mutation developed

Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models with the necessary mitochondrial ...

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