Mitochondria are considered to be the power plants of cells and are essential for human metabolism. Dysfunction in 40% of mitochondrial proteins are associated with human diseases, which is why mitochondria also play an important ...
Molecular & Computational biology
Jan 5, 2023
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38
Scientists at the University of Cologne have discovered how cells can eliminate mutated mitochondrial DNA (mtDNA). Due to their evolutionary descent from bacteria, mitochondria still have genetic material packaged in chromosome-like ...
Cell & Microbiology
Nov 16, 2022
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53
Investigators have discovered that outer mitochondrial membrane proteins regulate crosstalk between mitochondria and lysosomes, according to a Northwestern Medicine study published in the Journal of Cell Biology. These findings ...
Cell & Microbiology
Oct 26, 2022
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38
In a study using lab-grown cells, Johns Hopkins Medicine researchers specializing in aging report they have successfully delivered a common blood pressure drug directly to the inner membrane of mitochondria.
Bio & Medicine
Sep 20, 2022
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15
Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models with the necessary mitochondrial ...
Cell & Microbiology
Aug 25, 2022
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4
Researchers from the National Institutes of Health have developed a three-dimensional structure that allows them to see how and where disease mutations on the twinkle protein can lead to mitochondrial diseases. The protein ...
Molecular & Computational biology
Aug 5, 2022
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80
When something goes wrong in mitochondria, the tiny organelles that power cells, it can cause a bewildering variety of symptoms such as poor growth, fatigue and weakness, seizures, developmental and cognitive disabilities, ...
Cell & Microbiology
May 25, 2022
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154
Many age-related diseases share a common feature: the mitochondria of cells begin to malfunction. While the cause is not known, Buck Institute scientists have discovered a new mechanism of how mitochondria start to go wrong, ...
Cell & Microbiology
May 19, 2022
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53
We need zinc: one-tenth of the proteins in our cells require this metal for their normal functions in all aspects of cell metabolism.
Cell & Microbiology
May 17, 2022
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31
A research team from Cologne and Osnabrück has investigated in detail how messenger substances signal inflammation during the removal of damaged cells in the body. Using high-resolution microscopy methods, the researchers ...
Molecular & Computational biology
Feb 4, 2022
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