The energetic origins of life
Mapping subcellular temperature profiles with genetically-encoded thermosensors
Quality, quantity, and freshness in the reproductive game
Controlling the internal structure of mitochondria
The vital question: Why is life the way it is?
New mitochondrially-derived peptides show what they can do
Evolution at work: Even yeast mothers sacrifice all for their babies
A mother's willingness to sacrifice her own health and safety for the sake of her children is a common narrative across cultures – and by no means unique to humans alone. Female polar bears starve, dolphin ...
Amoeba offers key clue to photosynthetic evolution
(PhysOrg.com) -- The major difference between plant and animal cells is the photosynthetic process, which converts light energy into chemical energy. When light isn't available, energy is generated by breaking ...
Age-discrimination during cell division maintains the 'stem' in stem cells
A team of Whitehead Institute scientists has discovered that during division, stem cells distinguish between old and young mitochondria and allocate them disproportionately between daughter cells. As a result, ...
Brain tumor cells decimated by mitochondrial 'smart bomb'
An experimental drug that attacks brain tumor tissue by crippling the cells' energy source called the mitochondria has passed early tests in animal models and human tissue cultures, say Houston Methodist ...
New studies power legacy of UW-Madison research, 60 years later
Frederick Crane was a researcher under David E. Green in the mid-1950s, during the early days of the University of Wisconsin-Madison Enzyme Institute, when he made his defining discovery.
Team makes scientific history with new cellular connection
Researchers led by Dr. Helen McNeill at the Lunenfeld-Tanenbaum Research Institute have revealed an exciting and unusual biochemical connection. Their discovery has implications for diseases linked to mitochondria, ...
Team uses nanoparticles to enhance chemotherapy
(Phys.org) —University of Georgia researchers have developed a new formulation of cisplatin, a common chemotherapy drug, that significantly increases the drug's ability to target and destroy cancerous cells.
Fine tuning an old-school chemotherapy drug
First approved by the FDA in the 1970s, the chemotherapy drug cisplatin and its relative carboplatin remain mainstays of treatment for lung, head and neck, testicular and ovarian cancer. However, cisplatin's ...