In research that could ultimately lead to many new medicines, scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed a potentially general approach to design drugs from genome sequence. ...
Biochemistry
Feb 9, 2014
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0
Whenever it hears an unfamiliar song from a bird of the same species, a zebra finch stops chirping, hopping and grooming. It listens attentively for minutes at a time, occasionally cocking its head but otherwise immobile. ...
Plants & Animals
Jun 30, 2011
2
0
(PhysOrg.com) -- Researchers at the University of Pennsylvania have developed a new electronic method for detecting microRNA isolated from living cells. MicroRNAs are a class of small biomolecules that control gene expression ...
Bio & Medicine
Oct 26, 2010
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(PhysOrg.com) -- Yale University researchers have discovered a novel viral survival strategy, an insight that could help scientists better understand how viruses contribute to diseases such as cancer and AIDS.
Biochemistry
Jun 18, 2010
8
0
Ever since tiny bits of genetic material known as microRNA were first characterized in the early 1990s, scientists have been discovering just how important they are to regulating the activity of genes within cells.
Biotechnology
Apr 21, 2010
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0
The complexity of living organisms is encoded within their genes, but where do these genes come from? Researchers at the University of Helsinki resolved outstanding questions around the origin of small regulatory genes, and ...
Evolution
Dec 8, 2023
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2299
MicroRNAs are small molecules that regulate gene activity by binding to and destroying RNAs produced by the genes. More than 60% of all human genes are estimated to be regulated by microRNAs; therefore, it is not surprising ...
Cell & Microbiology
Sep 21, 2023
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23
A family of regulatory molecules, microRNAs, are key to the maintenance of fertility in both genders.
Cell & Microbiology
Sep 28, 2022
0
8
In a study from the lab of Whitehead Institute Member David Bartel, researchers have identified genetic sequences that can lead to the degradation of cellular regulators called microRNAs in the fruit fly Drosophila melanogaster. ...
Cell & Microbiology
Sep 27, 2022
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23
Researchers are pursuing ever-more sophisticated treatments to tackle lung cancer. Traditional chemotherapy can have serious side-effects throughout the body, so many new treatments are highly targeted. These methods allow ...
Bio & Medicine
Jun 30, 2022
0
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In genetics, microRNAs (miRNA) are single-stranded RNA molecules of 21-23 nucleotides in length, which regulate gene expression. miRNAs are encoded by genes from whose DNA they are transcribed but miRNAs are not translated into protein (i.e. they are non-coding RNAs); instead each primary transcript (a pri-miRNA) is processed into a short stem-loop structure called a pre-miRNA and finally into a functional miRNA. Mature miRNA molecules are partially complementary to one or more messenger RNA (mRNA) molecules, and their main function is to down-regulate gene expression. They were first described in 1993 by Lee and colleagues in the Victor Ambros lab , yet the term microRNA was only introduced in 2001 in a set of three articles in Science.
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