Ancient worm reveals way to destroy toxic cells in Huntington's disease
Insights from their study may provide a novel therapeutic approach for diseases such as Huntington's and Parkinson's.
Insights from their study may provide a novel therapeutic approach for diseases such as Huntington's and Parkinson's.
Molecular & Computational biology
Dec 7, 2019
1
902
Bee larvae develop into workers, in part, because their diet of pollen and honey, called beebread, is rich in plant regulatory molecules called microRNAs, which delay development and keep their ovaries inactive. Xi Chen of ...
Plants & Animals
Aug 31, 2017
0
1420
A team of student researchers from John Jay College of Criminal Justice has discovered human microRNA genes not shared with any other primate species and which may have played an important role in the unique evolution of ...
Evolution
Mar 8, 2022
0
446
The complexity of living organisms is encoded within their genes, but where do these genes come from? Researchers at the University of Helsinki resolved outstanding questions around the origin of small regulatory genes, and ...
Evolution
Dec 8, 2023
1
2299
A simple blood test could be used in the future to predict the health and productivity of dairy cows, research shows.
Plants & Animals
Sep 17, 2018
0
5
One of the major obstacles with treating cancer is that tumors can conscript the body's immune cells and make them work for them. Researchers at EPFL have now found a way to reclaim the corrupted immune cells, turn them into ...
Cell & Microbiology
Jun 13, 2016
0
133
(PhysOrg.com) -- Yale University researchers have discovered a novel viral survival strategy, an insight that could help scientists better understand how viruses contribute to diseases such as cancer and AIDS.
Biochemistry
Jun 18, 2010
8
0
(PhysOrg.com) -- Why do some plants blossom even when days are short and gray? Scientists at the Max Planck Institute for Developmental Biology have found the answer to this question: An endogenous mechanism allows them to ...
Plants & Animals
Aug 20, 2009
0
0
The Earth formed 4.5 billion years ago, and life less than a billion years after that. Although life as we know it is dependent on four major macromolecules—DNA, RNA, proteins and lipids—only one is thought to have been ...
Molecular & Computational biology
Nov 30, 2023
0
104
Early detection is vital for the effective treatment of cancer. In many cases, tell-tale biomarkers are present in the bloodstream long before outward symptoms become apparent. Early-stage cancers, for example, release tiny ...
Analytical Chemistry
Mar 8, 2013
0
0
In genetics, microRNAs (miRNA) are single-stranded RNA molecules of 21-23 nucleotides in length, which regulate gene expression. miRNAs are encoded by genes from whose DNA they are transcribed but miRNAs are not translated into protein (i.e. they are non-coding RNAs); instead each primary transcript (a pri-miRNA) is processed into a short stem-loop structure called a pre-miRNA and finally into a functional miRNA. Mature miRNA molecules are partially complementary to one or more messenger RNA (mRNA) molecules, and their main function is to down-regulate gene expression. They were first described in 1993 by Lee and colleagues in the Victor Ambros lab , yet the term microRNA was only introduced in 2001 in a set of three articles in Science.
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