News tagged with microrna
It's a trap! New laboratory technique captures microRNA targets
Human cells are thought to produce thousands of different microRNAs (miRNAs)—small pieces of genetic material that help determine which genes are turned on or off at a given time. miRNAs are an important ...
May 09, 2012 |
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Doubling the information from the Double Helix
(Phys.org) -- Our genes control many aspects of who we are — from the colour of our hair to our vulnerability to certain diseases — but how are the genes, and consequently the proteins they make ...
Apr 27, 2012 |
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Ultrasensitive particles offer new way to find cancer
About 10 years ago, scientists discovered a new type of genetic material called microRNA, which appears to turn genes on or off inside a cell. More recently, they found that these genetic snippets often go ...
Aug 31, 2011 |
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MicroRNAs in the songbird brain respond to new songs (w/ video)
Whenever it hears an unfamiliar song from a bird of the same species, a zebra finch stops chirping, hopping and grooming. It listens attentively for minutes at a time, occasionally cocking its head but otherwise ...
Jun 30, 2011 |
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Scientists investigate possible key to non-invasive prostate testing
The project, led by Chancellor's Postdoctoral Research Fellow Dr. Nham Tran and Head of the Translational Cancer Research Group Dr. Rosetta Martiniello-Wilks, will establish if microRNA collected from body fluids can signal ...
Feb 17, 2011 |
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Researchers reveal function of novel molecule that underlies human deafness
New research from the University of Sheffield has revealed that the molecular mechanism underlying deafness is caused by a mutation of a specific microRNA called miR-96. The discovery could provide the basis for treating ...
Medicine & Health / Medical research
Jan 21, 2011 |
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Discovery could shrink dengue-spreading mosquito population
Each year, dengue fever infects as many as 100 million people while yellow fever is responsible for about 30,000 deaths worldwide. Both diseases are spread by infected female Aedes aegypti mosquitoes, which ...
Dec 02, 2010 |
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Tiny RNA shown to cause multiple types of leukemia
(PhysOrg.com) -- Whitehead Institute researchers have shown in mouse models that overexpression of the microRNA 125b (miR-125b) can independently cause leukemia and accelerate the disease's progression. Their results are ...
Nov 29, 2010 |
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Too much of a good thing: Important mechanism in hormone-sensitive breast cancer uncovered
In two out of three breast tumors, extraordinarily high levels of the estrogen receptor ERalpha are found. Scientists of the German Cancer Research Center have now uncovered a mechanism which causes this overproduction. ...
Nov 23, 2010 |
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MicroRNA controls mammary gland development in mice
Hormones, growth factors and several proteins ensure that development occurs in the right way, at the right time. The components that cause breast development in mammals, for example, were thought to be largely ...
Nov 09, 2010 |
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Jekyll-Hyde microRNA binding variant linked to improved outcome in early-stage colorectal cancer
A variant site linked to poor outcome in advanced colorectal cancer has now been found to predict improved prognosis in early stages of cancer, according to research presented at the American Association for Cancer Research ...
Oct 28, 2010 |
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Scientists develop method for detecting microRNA from living cells
(PhysOrg.com) -- Researchers at the University of Pennsylvania have developed a new electronic method for detecting microRNA isolated from living cells. MicroRNAs are a class of small biomolecules that control ...
Nanotechnology / Bio & Medicine
Oct 26, 2010 |
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MicroRNAs dictate the Epstein-Barr virus' elaborate waiting game, cancer formation
While most commonly associated with mononucleosis, Epstein-Barr virus (EBV) has been linked to many diseases that affect people long after the initial infection takes place, including some forms of cancer. In the current ...
Oct 25, 2010 |
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Better cholesterol drugs may follow SLU researcher's breakthrough
Thanks to a discovery by a Saint Louis University researcher, scientists have identified an important microRNA that may allow us to better control cholesterol levels in blood.
Medicine & Health / Medical research
Oct 05, 2010 |
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Screening tool can detect colorectal cancer from a small blood sample
A new microRNA (miRNA) screening assay detected the majority of early-stage colorectal cancers with good specificity and sensitivity.
Sep 29, 2010 |
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MicroRNA
In genetics, microRNAs (miRNA) are single-stranded RNA molecules of 21-23 nucleotides in length, which regulate gene expression. miRNAs are encoded by genes from whose DNA they are transcribed but miRNAs are not translated into protein (i.e. they are non-coding RNAs); instead each primary transcript (a pri-miRNA) is processed into a short stem-loop structure called a pre-miRNA and finally into a functional miRNA. Mature miRNA molecules are partially complementary to one or more messenger RNA (mRNA) molecules, and their main function is to down-regulate gene expression. They were first described in 1993 by Lee and colleagues in the Victor Ambros lab , yet the term microRNA was only introduced in 2001 in a set of three articles in Science.
For more information about MicroRNA, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
