New chemistry makes 'magic' drug improvements easier
In the last decade, scientists discovered a quirk of drug chemistry: If you add on a simple one-carbon building block to a drug, it can make the drug more potent, less toxic, or more stable.
In the last decade, scientists discovered a quirk of drug chemistry: If you add on a simple one-carbon building block to a drug, it can make the drug more potent, less toxic, or more stable.
Biochemistry
Apr 23, 2021
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128
In molecules, there are certain groups of atoms that are able to rotate. This movement occurs under the influence of random stimuli from the environment, and is not continuous, but occurs in jumps. It is generally believed ...
Quantum Physics
Jun 1, 2017
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32
When exactly did oxygen first appear in Earth's atmosphere? Although many physical and chemical processes are thought to be responsible for that profound transformation, scientists have tried to answer at least part of that ...
Cell & Microbiology
May 6, 2010
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Although each and every one of us goes through it, ageing is a poorly understood process. Researchers have used a biomarker called the epigenetic clock to identify a gene that is closely linked to ageing in humans. The study, ...
Biotechnology
Aug 13, 2019
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43
One way cells can control the activities of their genes is by adding small chemical modifications to the DNA that determine which genes are turned on or off. Methyl groups are one of these chemical modifications or tags. ...
Molecular & Computational biology
Jul 1, 2022
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100
Susan Gasser and her group at the FMI have found the pathway through which eukaryotic organisms protect their genomes from rearrangements and deletions that arise from repetitive DNA. Human genomes, like those of simple animals ...
Biotechnology
Oct 10, 2016
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172
National Institute of Standards and Technology researchers at the Institute for Bioscience and Biotechnology Research have demonstrated the most precise method yet to measure the structural configuration of monoclonal antibodies ...
Analytical Chemistry
Apr 15, 2015
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22
Genetically modified bacteria could be used in air filters to extract pesticide vapors from polluted air thanks to work by researchers in China published this month in the International Journal of Environment and Pollution.
Cell & Microbiology
Apr 14, 2011
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Copper released into the environment from fungicides, brake pads, antifouling paints on boats and other sources may be contributing significantly to stratospheric ozone depletion, according to a new study from the University ...
Environment
Jan 14, 2022
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172
Two opposing teams battle it out to regulate gene expression on the DNA playing field. One, the activators, keeps DNA open to enzymes that transcribe DNA into RNA. Their repressor opponents antagonize that effort by twisting ...
Cell & Microbiology
Aug 26, 2012
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