New chemistry makes 'magic' drug improvements easier

In the last decade, scientists discovered a quirk of drug chemistry: If you add on a simple one-carbon building block to a drug, it can make the drug more potent, less toxic, or more stable.

Pinpointing the molecular mechanisms of ageing

Although each and every one of us goes through it, ageing is a poorly understood process. Researchers have used a biomarker called the epigenetic clock to identify a gene that is closely linked to ageing in humans. The study, ...

New method boosts the study of regulation of gene activity

One way cells can control the activities of their genes is by adding small chemical modifications to the DNA that determine which genes are turned on or off. Methyl groups are one of these chemical modifications or tags. ...

Epigenetic repression suppresses genomic instability

Susan Gasser and her group at the FMI have found the pathway through which eukaryotic organisms protect their genomes from rearrangements and deletions that arise from repetitive DNA. Human genomes, like those of simple animals ...

NMR 'fingerprinting' for monoclonal antibodies

National Institute of Standards and Technology researchers at the Institute for Bioscience and Biotechnology Research have demonstrated the most precise method yet to measure the structural configuration of monoclonal antibodies ...

Filtering out pesticides with E. coli

Genetically modified bacteria could be used in air filters to extract pesticide vapors from polluted air thanks to work by researchers in China published this month in the International Journal of Environment and Pollution.

Copper-based chemicals may be contributing to ozone depletion

Copper released into the environment from fungicides, brake pads, antifouling paints on boats and other sources may be contributing significantly to stratospheric ozone depletion, according to a new study from the University ...

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