News tagged with metastatic tumors
Researchers unravel biochemical factor important in tumor metastasis
A protein called "fascin" appears to play a critical transformation role in TGF beta mediated tumor metastasis, say researchers at Moffitt Cancer Center in Tampa, Fla., who published a study in a recent issue of the Journal of ...
Nov 09, 2011 |
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Study finds protein critical to breast cancer cell proliferation, migration
Researchers have found that a protein linked to cell division and migration and tied to increased cell proliferation in ovarian tumors is also present at high levels in breast cancer specimens and cell lines. The protein, ...
Sep 15, 2011 |
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Researchers uncover new risk factors for brain metastases in breast cancer patients
Nearly one-fifth of all metastatic breast cancer patients develop brain metastases and have significantly shorter overall survival than patients who do not have brain involvement. One way to improve the affected patients' ...
Dec 09, 2010 |
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Study shows patient-specific vaccines for metastatic melanoma may induce durable complete regression
Hoag Memorial Hospital Presbyterian recently announced encouraging clinical study results for patient-specific vaccine therapy to treat metastatic melanoma. The study is ongoing, but the report concludes that patient-specific ...
Sep 27, 2010 |
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Targeted drug leads to regression of metastatic melanoma with mutated BRAF gene
Use of an experimental targeted drug to treat metastatic melanoma tumors with a specific genetic signature was successful in more than 80 percent of patients in a phase 1 clinical trial. Results of the trial of PLX4032, ...
Aug 25, 2010 |
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Survival in metastatic breast cancer directly linked to circulating tumor cells
A new study of metastatic breast cancer shows that the number of circulating tumor cells patients have in their blood directly correlates with the length of their survival. Reported at the IMPAKT Breast Cancer Conference ...
May 06, 2010 |
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Enzyme found to be a predictive marker of survival in head and neck cancer
Most treatment for advanced head and neck cancer requires chemotherapy with a drug called cisplatin, an inorganic platinum agent that inhibits cell growth. A substantial number of patients do not respond well to this therapy, ...
Apr 19, 2010 |
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Decoding tumor genomes reveals clues to spread of deadly breast cancer
Using powerful DNA sequencing technology to decode the genomes of cancer patients, scientists at Washington University School of Medicine in St. Louis are getting an unprecedented look at the genetic basis of a highly lethal ...
Apr 14, 2010 |
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Why metastasic cells migrate
Migration ability of metastatic cells is not due to an altered mechanism of tumor cells but to a natural capacity of healthy cells. The results could help to identify potential strategies for metastasis inhibition.
Mar 29, 2010 |
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Novel personalized medicine trial launched for metastatic colorectal cancer
Imagine if treatments for disease could be based not on a patient's diagnosis but instead on the characteristics of their tissue. By identifying and decoding the cryptic messages hidden deep inside the human proteome, scientists ...
Jan 15, 2010 |
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Investigational agent reduces tumor resistance to breast cancer therapy
Researchers at Georgetown Lombardi Comprehensive Cancer Center have found a way to cleverly override signals that tell breast cancer cells to keep surviving in the face of anticancer treatment. The investigational agent they ...
Jan 06, 2010 |
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Human Mdm2: A new molecular link to late-stage metastatic breast cancer
A large proportion of late-stage breast cancers that have spread to other parts of the body (metastatic breast cancers) are characterized by overexpression of the protein Mdm2.
Dec 02, 2009 |
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Low-dose estrogen shown safe and effective for metastatic breast cancer
When estrogen-lowering drugs no longer control metastatic breast cancer, the opposite strategy might work. Raising estrogen levels benefited 30 percent of women whose metastatic breast cancer no longer responded to standard ...
Aug 18, 2009 |
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Preventing Prostate Cancer to Bone Metastasis
(PhysOrg.com) -- In new research on prostate cancer to bone metastasis, Dr. Phillip Trackman of Boston University Henry M. Goldman School of Dental Medicine explains that the lysyl oxidase pro-peptide (LOX-PP) inhibits prostate ...
Jul 13, 2009 |
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Lithium may help radiation target cancer, spare healthy tissue
Vanderbilt-Ingram Cancer Center investigators have uncovered a mechanism that helps explain how lithium, a drug widely used to treat bipolar mood disorder, also protects the brain from damage that occurs during radiation ...
May 04, 2009 |
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