While computer simulations of how the body metabolises drugs save both time and money, the best results when developing new drugs come from combining such simulations with laboratory experiments, reveals a ...
Oct 04, 2010
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Scientists at The Scripps Research Institute have designed a new molecular test that will allow researchers to look for potential drugs targeting a human metabolic enzyme believed to stimulate the appetite and play a role ...
Sep 16, 2010
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(PhysOrg.com) -- Zemer Gitai, an assistant professor of molecular biology at Princeton University, members of his laboratory, and scientists from the California Institute of Technology have published results in Nature Ce ...
Aug 02, 2010
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Echinacea has been used for hundreds of years as an herbal remedy to prevent or treat colds, and today it is among the most commonly used herbal medicines in North America. However, in spite of its popularity, ...
Jun 29, 2010
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Protein phosphorylation is a process by which proteins are flipped from one activation state to another. It is a crucial function for most living beings, since phosphorylation controls nearly every cellular ...
Mar 24, 2010
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Research led by Wayne L. Backes, PhD, Professor of Pharmacology and Associate Dean for Research at LSU Health Sciences Center New Orleans School of Medicine, has found that drug metabolism depends not only upon which enzymes ...
Mar 17, 2010
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It is not unusual to hear people blame their metabolism after gaining a few pounds. But changes in metabolism - the process that shapes how our bodies turn food into energy -- can have much more sinister effects ...
Feb 18, 2010
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(PhysOrg.com) -- A research team led by biochemist Scott Garman at the University of Massachusetts Amherst has for the first time determined the mechanism of one of the cell’s 'recycling' enzymes, human alpha-galactosidase ...
Feb 02, 2010
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Even the simplest cell appears to be far more complex than researchers had imagined. In a series of three articles in the journal Science, researchers including Vera van Noort at the European Molecular Biology Laboratory (EMBL) ...
Dec 28, 2009
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Agios Pharmaceuticals today announced that its scientists have established, for the first time, that the mutated IDH1 gene has a novel enzyme activity consistent with a cancer-causing gene, or oncogene. This breakthrough ...
Nov 22, 2009
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In a major advance in obesity and diabetes research, Yale School of Medicine scientists have found that reducing levels of a key enzyme in the brain decreased appetites and increased energy levels.
Jul 20, 2009
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A Boston University-led research team has identified the structural underpinnings of a widely-known enzyme -- acetoacetate decarboxylase (AADase) -- that was first described correctly more than 43 years ago including how ...
May 20, 2009
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Scientists at the Gladstone Institutes of Cardiovascular Disease (GICD) have found that a key enzyme involved in absorbing fat may also be a key to reducing it. The enzyme, acyl CoA: monoacylglycerol acyltransferase 2 or ...
Mar 16, 2009
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(PhysOrg.com) -- UC Irvine researchers have discovered that circadian rhythms - our own body clock - regulate energy levels in cells. The findings have far-reaching implications, from providing greater insights ...
Mar 12, 2009
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