Researchers have developed a new method of detecting a metabolic disease that affects dairy cows after calving. The aim is to determine whether cows are at risk of contracting the disease before they actually become sick.
Agriculture
Sep 5, 2023
0
107
A study of mice found that dietary sugar alters the gut microbiome, setting off a chain of events that leads to metabolic disease, pre-diabetes, and weight gain.
Cell & Microbiology
Aug 29, 2022
0
814
Diabetes is a metabolic disease defined by high blood sugar levels, and can affect organs such as the heart, eyes and kidneys. According to the World Health Organization, over 420 million people suffer from this condition ...
Analytical Chemistry
May 2, 2017
0
24
(PhysOrg.com) -- Diabetes is the most prevalent metabolic disease in developed countries and one that engenders - in addition to its high fatality - enormous health care costs. The physiological meaning of the ‘feel-good’ ...
Biochemistry
Oct 28, 2009
0
1
During the pandemic, it has become evident that people with cardiovascular disease and obesity are at much higher risk of developing very severe, even fatal COVID-19 disease. Researchers at Karolinska Institutet have identified ...
Molecular & Computational biology
Oct 8, 2021
0
970
The bones of sailors who sailed on Henry VIII's Mary Rose ship have been analysed with the help of new laser technology to identify evidence of bone disease.
Archaeology
Dec 17, 2014
0
0
Many diseases derive from problems with cellular respiration, the process through which cells extract energy from nutrients. Researchers at the Swedish medical university Karolinska Institutet have now discovered a new function ...
Cell & Microbiology
Apr 8, 2009
0
1
Proven to protect against a wide array of diseases, exercise may be the most powerful anti-aging intervention known to science. However, while physical activity can improve health during aging, its beneficial effects inevitably ...
Cell & Microbiology
Jan 5, 2023
1
87
Inflammation. The word typically has a negative connotation. Arthritis … infection … numerous maladies come to mind. But a Kansas State University researcher found that inflammation that occurs naturally in dairy cows ...
Plants & Animals
Jul 12, 2013
0
0
(PhysOrg.com) -- After taking a small dose of inorganic nitrate for three days, healthy people consume less oxygen while riding an exercise bike. A new study in the February issue of Cell Metabolism traces that improved performance ...
Cell & Microbiology
Feb 1, 2011
10
0
Inborn errors of metabolism comprise a large class of genetic diseases involving disorders of metabolism. The majority are due to defects of single genes that code for enzymes that facilitate conversion of various substances (substrates) into others (products). In most of the disorders, problems arise due to accumulation of substances which are toxic or interfere with normal function, or to the effects of reduced ability to synthesize essential compounds. Inborn errors of metabolism are now often referred to as congenital metabolic diseases or inherited metabolic diseases, and these terms are considered synonymous.
The term inborn error of metabolism was coined by a British physician, Archibald Garrod (1857-1936), in the early 20th century (1908). He is known for work that prefigured the "one gene, one enzyme" hypothesis, based on his studies on the nature and inheritance of alkaptonuria. His seminal text, Inborn Errors of Metabolism was published in 1923.
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