News tagged with membrane channel
Unusual protein helps regulate key cell communication pathway
Charged atoms, or ions, move through tiny pores, or channels, embedded in cell membranes, generating the electrical signals that allow cells to communicate with one another. In new research, scientists have ...
Apr 23, 2012 |
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Bioengineers develop artificial chip for testing how drugs interact with ion channels
(Phys.org) -- Ion channels, proteins embedded in cell membranes, are central to many of the human body's physiological processes, including cardiac activity. For this reason, they are also important targets for cardiac drugs. ...
Apr 10, 2012 |
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Research shows how the body senses a range of hot temperatures
The winter sun feels welcome, but not so a summer sunburn. Research over the past 20 years has shown that proteins on the surface of nerve cells enable the body to sense several different temperatures. Now scientists have ...
Mar 02, 2012 |
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Study shows Alzheimer's disease-related peptides form toxic calcium channels in the plasma membrane
Alzheimer's disease is triggered by the inappropriate processing of amyloid precursor protein to generate excess amounts of short peptide fragments called A-beta. For many years, the neurodegeneration associated with Alzheimer's ...
Oct 24, 2011 |
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How plants sense touch, gravity and other physical forces
(PhysOrg.com) -- At the bottom of plants' ability to sense touch, gravity or a nearby trellis are mechanosensitive channels, pores through the cells' plasma membrane that are opened and closed by the deformation ...
Oct 21, 2011 |
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Scientists model the pathways of pain-blocking meds
Benzocaine, a commonly used local anesthetic, may more easily wiggle into a cell's membrane when the membrane is made up of compounds that carry a negative charge, a new study shows. The finding could help scientists piece ...
Sep 26, 2011 |
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Researchers get a first look at the mechanics of membrane proteins
In two new studies, researchers provide the first detailed view of the elaborate chemical and mechanical interactions that allow the ribosome – the cell's protein-building machinery – to insert a ...
Apr 17, 2011 |
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Scientists crack molecular code regulating neuronal excitability
A key question in protein biochemistry is how proteins recognize "correct" interaction partners in a sea of cellular factors. Nowhere is that more critical to know than in the brain, where interactions governing ...
Medicine & Health / Medical research
Mar 22, 2011 |
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Newly identified spider toxin may help uncover novel ways of treating pain and human diseases
Spider venom toxins are useful tools for exploring how ion channels operate in the body. These channels control the flow of ions across cell membranes, and are key components in a wide variety of biological processes and ...
Mar 09, 2011 |
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A second pathway for antidepressants: New fluorescent assay reveals TREK1 mechanism
(PhysOrg.com) -- Using a unique and relatively simple cell-based fluorescent assay they developed, scientists with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) ...
Medicine & Health / Medical research
Feb 07, 2011 |
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Neuroscientists learn how channels fine-tune neuronal excitability
Scientists in the Hotchkiss Brain Institute at the Faculty of Medicine, University of Calgary, have discovered a new mechanism that nerve cells (neurons) use to fine-tune their electrical output. The exciting discovery, published ...
Medicine & Health / Neuroscience
Jan 26, 2011 |
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At last, a living model for an important body channel
(PhysOrg.com) -- Ion channels provide a way for key molecules to cross into cells, are the means for many swift physical reactions and regulate the movement of fluid across internal cavities in our bodies. When chloride ions ...
Oct 07, 2010 |
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German researchers use light to make the heart stumble
Tobias Brugmann and his colleagues from the University of Bonn's Institute of Physiology I used a so-called "channelrhodopsin" for their experiments, which is a type of light sensor. At the same time, it can act as an ion ...
Medicine & Health / Medical research
Oct 04, 2010 |
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'Wonder gene' found to affect blood pressure
(PhysOrg.com) -- Scientists have identified an important gene that regulates the function of the muscle cells in arteries and thereby helps determine blood pressure.
Jul 01, 2010 |
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How bacteria make syringes: Scientists reconstruct bacterial transport channel in test tube
For a successful infection, bacteria must outwit the immune system of the host. To this aim, they deliver so-called virulence factors through a transport channel located in the bacterial membrane. In some ...
Jun 13, 2010 |
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