Learning from endangered zebra stem cells

Scientists from Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) and Wildlife Research Centre have produced stem cells from the endangered Grévy's zebra using human reprogramming factors. Further ...

Mutations across animal kingdom shed new light on aging

The first study to compare the accumulation of mutations across many animal species has shed new light on decades-old questions about the role of these genetic changes in aging and cancer. Researchers from the Wellcome Sanger ...

Stabilizing chromosomes to tackle tumors

Cells use RNA as a versatile tool to regulate the activity of their genes. Small snippets of RNA can fine-tune how much protein is produced from various genes; some small RNAs can shut genes off altogether. An enzyme called ...

Pioneering new technique to barcode cells

Scientists have developed a pioneering new technique to barcode individual cells more accurately and efficiently—which could help pave the way for quicker disease diagnosis. 

The Spatial Mouse Atlas: New insights into cell fate

High-resolution gene expression maps have been combined with single-cell genomics data to create a new resource for studying how cells adopt different identities during mammalian development. The Spatial Mouse Atlas is the ...

New discovery shows human cells can write RNA sequences into DNA

Cells contain machinery that duplicates DNA into a new set that goes into a newly formed cell. That same class of machines, called polymerases, also build RNA messages, which are like notes copied from the central DNA repository ...

How human cells and pathogenic shigella engage in battle

One member of a large protein family that is known to stop the spread of bacterial infections by prompting infected human cells to self-destruct appears to kill the infectious bacteria instead, a new study led by UT Southwestern ...

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