Smart drug design to prevent malaria treatment resistance
Malaria treatment resistance could be avoided by studying how resistance evolves during drug development, according to a new paper published in Cell Chemical Biology.
Malaria treatment resistance could be avoided by studying how resistance evolves during drug development, according to a new paper published in Cell Chemical Biology.
Biochemistry
May 9, 2019
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22
Mosquitoes won't fly anywhere near the sweet wormwood herb (Artemisia annua), so it makes perfect sense that a chemical compound produced by the plant has become the first line of treatment against malaria.
Plants & Animals
Apr 9, 2019
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9
The role of mosquitoes in spreading malaria is the biggest factor behind a recent study that found them to be the 'World's Deadliest Animal'. It is particularly concerning that current measures to control them (the most important ...
Ecology
Mar 28, 2019
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10
An experimental drug, called DSM265, cured seven volunteers of a Plasmodium falciparum infection, a malaria parasite that is a major cause of morbidity and mortality worldwide. The goal of this research is to find a cure ...
Cell & Microbiology
Mar 11, 2019
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4
For decades, one of the strongest weapons against malaria has been a one-two punch: low-tech mosquito bed nets to physically block biting, treated with deadly insecticides to kill the mosquitoes.
Cell & Microbiology
Mar 11, 2019
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6
Simple folded sheets of waxed paper could help bring affordable, reliable field tests for diseases such as malaria to remote parts of the developing world, scientists say.
Analytical Chemistry
Feb 20, 2019
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27
The anopheline mosquitoes that carry malaria were present 100 million years ago, new research shows, potentially shedding fresh light on the history of a disease that continues to kill more than 400,000 people annually.
Plants & Animals
Feb 11, 2019
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292
Scientists at the Institute of Genome Sciences (IGS) at the University of Maryland School of Medicine (UMSOM) have developed a novel way with genome sequences to study and better understand transmission, treat and ultimately ...
Biotechnology
Feb 8, 2019
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289
An international research team led by scientists at the University of California, Riverside, and the La Jolla Institute for Immunology has found that malaria parasite genomes are shaped by parasite-specific gene families, ...
Cell & Microbiology
Feb 4, 2019
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173
Disrupting two genes involved in the preservation of RNA molecules inhibits the ability of the male form of the malaria parasite to mature and be transmitted from human blood into mosquitoes, interrupting a key stage in the ...
Cell & Microbiology
Jan 31, 2019
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78