News tagged with macrophages
Salmonella infection, but not as we know it
Researchers at Cambridge University have shed new light on a common food poisoning bug. Using real-time video microscopy, coupled with mathematical modelling, they have changed our assumptions about Salmonella and how it ...
Apr 25, 2012 |
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Research shows why one bacterial infection is so deadly in cystic fibrosis patients
Scientists have found why a certain type of bacteria, harmless in healthy people, is so deadly to patients with cystic fibrosis.
Apr 23, 2012 |
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Pigeons' navigation skill not down to iron-rich beak cells: study
The theory that pigeons' famous skill at navigation is down to iron-rich nerve cells in their beaks has been disproved by a new study published in Nature.
Apr 11, 2012 |
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Toxins from diseased brain cells make diseases of the brain even worse
Sometimes our immune defence attacks our own cells. When this happens in the brain we see neurodegenerative diseases such as dementia, Alzheimer's and Parkinson's disease. But if the the immune defence is inhibited, the results ...
Feb 22, 2012 |
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Carbon black nanoparticles can cause cell death
Researchers from the University of Iowa Roy J. and Lucille A. Carver College of Medicine have found that inhaled carbon black nanoparticles create a double source of inflammation in the lungs.
Nanotechnology / Bio & Medicine
May 18, 2011 |
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Call of the riled: Stress signal in cancer cells triggers similar response in other cells, aiding tumor growth
Researchers at the University of California, San Diego School of Medicine say a "stress response" mechanism used by normal cells to cope with harsh or demanding conditions is exploited by cancer cells, which ...
Apr 04, 2011 |
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Making viruses pass for 'safe'
Viruses can penetrate every part of the body, making them potentially good tools for gene therapy or drug delivery. But with our immune system primed to seek and destroy these foreign invaders, delivering therapies with viruses ...
Medicine & Health / Medical research
Mar 08, 2011 |
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An Alzheimer's vaccine in a nasal spray
One in eight Americans will fall prey to Alzheimer's disease at some point in their life, current statistics say. Because Alzheimer's is associated with vascular damage in the brain, many of them will succumb through a painful ...
Medicine & Health / Medical research
Feb 28, 2011 |
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Breast cancer cells outsmart the immune system and thrive
Scientists discovered a new way breast cancer cells dodge the immune system and promote tumor growth, providing a fresh treatment target in the fight against the disease. While comparable mechanisms to avoid the immune system ...
Feb 01, 2011 |
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Scientists find the 'master switch' for key immune cells in inflammatory diseases
(PhysOrg.com) -- Scientists have identified a protein that acts as a "master switch" in certain white blood cells, determining whether they promote or inhibit inflammation. The study, published in the journal ...
Medicine & Health / Medical research
Jan 16, 2011 |
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Steering cancer inflammation to inhibit tumor growth and spread
Most cancer tissues are invaded by inflammatory cells that either stimulate or inhibit the growth of the tumor, depending on what immune cells are involved. Now a Swedish-Belgian research team has shown that a protein that ...
Jan 06, 2011 |
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Breast inflammation is key to cancer growth, researchers say
It took 12 years and a creation of a highly sophisticated transgenic mouse, but researchers at Kimmel Cancer Center at Jefferson have finally proven a long suspected theory: Inflammation in the breast is key to the development ...
Dec 15, 2010 |
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Immune system changes linked to inflammatory bowel disease revealed
Scientists at the Virginia Bioinformatics Institute at Virginia Tech have discovered some of the key molecular events in the immune system that contribute to inflammatory bowel disease. The results, which help researchers ...
Medicine & Health / Medical research
Dec 09, 2010 |
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Researchers describe first functioning 'lipidome' of mouse macrophage
For the first time, scientists have described not only the identities and quantities of fat species in a living mammalian cell in this case, a mouse macrophage or white blood cell but they also ...
Dec 01, 2010 |
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Source of protection against saturated fat found
A new report in the December Cell Metabolism identifies a protein without which diets high in saturated fat lead to a massive inflammatory response that can prove fatal. The studies in mice suggest that deficiencies in thi ...
Medicine & Health / Medical research
Nov 30, 2010 |
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Macrophage
Macrophages (Greek: big eaters, from makros "large" + phagein "eat"; abbr. MΦ) are white blood cells within tissues, produced by the division of monocytes. Human macrophages are about 21 micrometres in diameter. Monocytes and macrophages are phagocytes, acting in both non-specific defense (or innate immunity) as well as to help initiate specific defense mechanisms (or adaptive immunity) of vertebrate animals. Their role is to phagocytose (engulf and then digest) cellular debris and pathogens either as stationary or as mobile cells, and to stimulate lymphocytes and other immune cells to respond to the pathogen. They can be identified by specific expression of a number of proteins including CD14, CD11b, F4/80 (mice)/EMR1 (human), Lysozyme M, MAC-1/MAC-3 and CD68 by flow cytometry or immunohistochemical staining. They move by action of Amoeboid movement.
For more information about Macrophage, read the full article at
Wikipedia.
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