Atomic view of nature's amazing molecular machines at work

Researchers from the MPSD's Department of Atomically Resolved Dynamics at the Center for Free-Electron Laser Science, the Centre for Ultrafast Imaging (all in Hamburg), the University of Toronto in Canada and the ETH in Zurich, ...

Doing more with less; in cellulo structure determinations

Anyone involved in macromolecular crystallography will know that for many years scientists have had to rely on a multi-stage process utilizing protein, usually expressed in engineered cells, which is then extracted and purified ...

Scientists use CLS to identify key protein in stopping viruses

(Phys.org)—Using the Canadian Light Source (CLS) synchrotron, researchers have determined the structure of a key protein that stops viruses from spreading, an important step towards developing new ways of fighting viral ...

A new approach for solving protein structures

(Phys.org)—Using synchrotron x-ray beams to solve the molecular structures of proteins and other large biological molecules has yielded many advances in medicine, such as drug therapies for cancer. Improvements in the techniques ...

SLAC X-rays help discover new drug against melanoma

It was front page news around the world: a drug designed to disrupt malignant melanoma, the deadliest form of skin cancer, was so successful in its latest round of testing in humans that the tests were halted – like ...

Biologists reveal structure of cell nucleus 'gatekeeper'

(PhysOrg.com) -- Biologists led by associate professor Thomas Schwartz (MIT) have worked out a rudimentary architectural plan for the nuclear pore complex (NPC), the gatekeeper of the cell's nucleus.