News tagged with lysosomal enzyme
New test spots early signs of mucopolysaccharidoses -- inherited metabolic disorders
A team of scientists, led by researchers at the University of California, San Diego School of Medicine and Zacharon Pharmaceuticals, have developed a simple, reliable test for identifying biomarkers for mucopolysaccharidoses ...
Jan 08, 2012 |
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Biochemists Provide New Key for Treating Fabry Disease, a Rare Childhood Disorder
(PhysOrg.com) -- A research team led by biochemist Scott Garman at the University of Massachusetts Amherst has for the first time determined the mechanism of one of the cell’s 'recycling' enzymes, human alpha-galactosidase ...
Feb 02, 2010 |
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Scientists successfully reprogram blood cells
Researchers have transplanted genetically modified hematopoietic stem cells into mice so that their developing red blood cells produce a critical lysosomal enzyme -preventing or reducing organ and central nervous system damage ...
Nov 09, 2009 |
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Inventive approach may improve enzyme replacement therapy for Fabry disease
A new study uses a creative structure-based remodeling strategy to design a therapeutic protein that exhibits significant advantages over currently available treatments for a rare disease that often leads to cardiac and renal ...
Oct 22, 2009 |
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Search results for lysosomal enzyme
Molecular alternatives to DNA, RNA offer new insight into life's origins
Living systems owe their existence to a pair of information-carrying molecules: DNA and RNA. These fundamental chemical forms possess two features essential for life: they display heredity—meaning they can encode and ...
Apr 19, 2012 |
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Spectroscopic evidence for the unusual handedness of a mammalian lipid may advance our understanding of evolution
Phospholipids are the main constituents of the cellular membranes in all organisms, ranging from single-celled archaea to highly complex plants and mammals. According to conventional wisdom, the chemical backbone ...
Mar 23, 2012 |
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Biochemists develop promising new treatment direction for rare metabolic diseases
A research team led by biochemist Scott Garman at the University of Massachusetts Amherst has discovered a key interaction at the heart of a promising new treatment for a rare childhood metabolic disorder ...
Dec 22, 2011 |
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Unraveling Batten disease
Waste management is a big issue anywhere, but at the cellular level it can be a matter of life and death. A Weizmann Institute study, published in the Journal of Cell Biology, has revealed what causes a molecular waste contai ...
Nov 02, 2011 |
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Orchestrator of waste removal rescues cells that can't manage their trash
Just as we must take out the trash to keep our homes clean and safe, it is essential that our cells have mechanisms for dealing with wastes and worn-out proteins. When these processes are not working properly, unwanted debris ...
Sep 01, 2011 |
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A possible fix for misfolding proteins
(PhysOrg.com) -- Troubled proteins in need of rescue may someday have a champion in a common drug used to treat high blood pressure.
Jun 24, 2011 |
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Nanoparticle therapeutics might help people suffering from hearing disorders
For millions of people hearing disorders make a negative impact on their lives. Scientists are looking into new ways of treating hearing disorders, by using different sorts of nanoparticles as original inner ear delivery ...
Nanotechnology / Bio & Medicine
Jun 13, 2011 |
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New marker found for Sanfilippo disease
Sanfilippo disease is a rare disorder caused by the failure of enzymes to break down specific kinds of complex carbohydrates, resulting in their accumulation in cells and often severe physical and neurological ...
Feb 28, 2011 |
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New cell death mechanism has implications for breast cancer treatments
(PhysOrg.com) -- A novel mechanism of cell death that occurs in mammalian organisms has been revealed by researchers at the University of Cambridge.
Feb 25, 2011 |
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Targeted particle fools brain's guardian to reach tumors
A targeted delivery combination selectively crosses the tight barrier that protects the brain from the bloodstream to home in on and bind to brain tumors, a research team led by scientists from The University of Texas MD ...
Feb 01, 2011 |
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List of search results for lysosomal enzyme
