News tagged with liver metabolism

Alcohol tolerance 'switch' found

Researchers at North Carolina State University have found a genetic "switch" in fruit flies that plays an important role in making flies more tolerant to alcohol.

Medicine & Health / Genetics

created Oct 21, 2009 | popularity not rated yet | comments 0

Researchers engineer metabolic pathway in mice to prevent diet-induced obesity

In recent years, obesity has taken on epidemic proportions in developed nations, contributing significantly to major medical problems, early death and rising health care costs. According to Centers for Disease Control and ...

Medicine & Health / Medical research

created Jun 02, 2009 | popularity not rated yet | comments 0

Fat-free diet reduces liver fat in fat-free mice

Researchers at UT Southwestern Medical Center have uncovered crucial clues about a paradoxical disease in which patients with no body fat develop many of the health complications usually found in obese people.

Biology /

created Feb 03, 2009 | popularity not rated yet | comments 0

Liver parasite lacks key genes for fatty acid synthesis: Genome sequencing of Clonorchis sinensis

The human liver fluke Clonorchis sinensis affects more than 35 million people in South East Asia and 15 million in China. Infection by this parasite causes clonorchiasis. Repeated or chronic infection can lead to serious diseas ...

Biology / Biotechnology

created Oct 24, 2011 | popularity not rated yet | comments 0

Good housekeeping maintains a healthy liver

Differences in the levels of two key metabolic enzymes may explain why some people are more susceptible to liver damage, according to a study in the October 17 issue of the Journal of Cell Biology.

Biology / Cell & Microbiology

created Oct 17, 2011 | popularity 4 / 5 (1) | comments 0

Getting to the root of fatty liver disease

Researchers have identified a molecular switch that appears to be a common feature in the development of fatty liver disease. The discovery made in mice is consistent with data from human patients, suggesting ...

Medicine & Health / Medical research

created Apr 05, 2011 | popularity not rated yet | comments 0

Study finds cholesterol regulator plays key role in development of liver scarring, cirrhosis

UCLA researchers have demonstrated that a key regulator of cholesterol and fat metabolism in the liver also plays an important role in the development of liver fibrosis -- the build-up of collagen scar tissue ...

Medicine & Health / Medical research

created Mar 30, 2011 | popularity 5 / 5 (1) | comments 0

New gene sites affecting nonalcoholic fatty liver disease discovered

NAFLD is a condition where fat accumulates in the liver (steatosis) and can lead to liver inflammation (nonalcoholic steatohepatitis or NASH) and permanent liver damage (fibrosis/cirrhosis). NAFLD affects anywhere from 11% ...

Medicine & Health / Genetics

created Mar 10, 2011 | popularity not rated yet | comments 0

Liver, dietary proteins key in fertility

When you think about organs with an important role in reproduction, the liver most likely doesn't spring to mind. But a new report in the February issue of Cell Metabolism, a Cell Press publication, shows that estrogen recept ...

Medicine & Health / Medical research

created Feb 01, 2011 | popularity not rated yet | comments 0

SRC-1 controls liver's 'sweet spot' for glucose production

SRC-1 (steroid receptor coactivator) orchestrates glucose production in the liver, regulating the activity of a cascade of enzymes that turns sugar production on and off in the liver, said Baylor College of Medicine and Duke ...

Medicine & Health / Medical research

created Nov 30, 2010 | popularity not rated yet | comments 0

Scientists identify proteins that ensure iron balance

(PhysOrg.com) -- Most organisms need iron to survive, but too much iron is toxic, and can cause fatal organ failure. The same is true inside cells, where iron balance must also be maintained. In a study published today in ...

Chemistry / Biochemistry

created Aug 03, 2010 | popularity 5 / 5 (1) | comments 0

High fructose, trans fats lead to significant liver disease, says study

Scientists at Cincinnati Children's Hospital Medical Center have discovered that a diet with high levels of fructose - levels equivalent to that in high fructose corn syrup - and of trans fats not only increases obesity, ...

Medicine & Health / Medical research

created Jun 22, 2010 | popularity not rated yet | comments 0

New data show breakthrough microRNA-targeted therapy holds promise as new treatment for hepatitis C

A study published online in this week's Science shows that SPC3649, a breakthrough microRNA-targeted therapy developed by Santaris Pharma A/S, holds promise as a novel treatment for patients infected with the Hepatitis C viru ...

Medicine & Health / Diseases, Conditions, Syndromes

created Dec 03, 2009 | popularity 5 / 5 (2) | comments 0

Common gene variant found to regulate iron levels

(PhysOrg.com) -- An international research team including researchers at UQ's Diamantina Institute and the Queensland Institute of Medical Research has identified a new variant of a gene that helps to regulate iron and haemoglobin ...

Medicine & Health / Genetics

created Oct 13, 2009 | popularity 5 / 5 (1) | comments 0

Low-fat diet helps genetically predisposed animals avoid liver cancer

In a study comparing two strains of mice, one susceptible to developing cancer and the other not, researchers found that a high-fat diet predisposed the cancer-susceptible strain to liver cancer, and that by switching to ...

Medicine & Health / Genetics

created Jun 12, 2009 | popularity not rated yet | comments 1