News tagged with liver metabolism
Liver parasite lacks key genes for fatty acid synthesis: Genome sequencing of Clonorchis sinensis
The human liver fluke Clonorchis sinensis affects more than 35 million people in South East Asia and 15 million in China. Infection by this parasite causes clonorchiasis. Repeated or chronic infection can lead to serious diseas ...
Oct 24, 2011 |
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Good housekeeping maintains a healthy liver
Differences in the levels of two key metabolic enzymes may explain why some people are more susceptible to liver damage, according to a study in the October 17 issue of the Journal of Cell Biology.
Oct 17, 2011 |
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Getting to the root of fatty liver disease
Researchers have identified a molecular switch that appears to be a common feature in the development of fatty liver disease. The discovery made in mice is consistent with data from human patients, suggesting ...
Medicine & Health / Medical research
Apr 05, 2011 |
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Study finds cholesterol regulator plays key role in development of liver scarring, cirrhosis
UCLA researchers have demonstrated that a key regulator of cholesterol and fat metabolism in the liver also plays an important role in the development of liver fibrosis -- the build-up of collagen scar tissue ...
Medicine & Health / Medical research
Mar 30, 2011 |
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New gene sites affecting nonalcoholic fatty liver disease discovered
NAFLD is a condition where fat accumulates in the liver (steatosis) and can lead to liver inflammation (nonalcoholic steatohepatitis or NASH) and permanent liver damage (fibrosis/cirrhosis). NAFLD affects anywhere from 11% ...
Mar 10, 2011 |
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Liver, dietary proteins key in fertility
When you think about organs with an important role in reproduction, the liver most likely doesn't spring to mind. But a new report in the February issue of Cell Metabolism, a Cell Press publication, shows that estrogen recept ...
Medicine & Health / Medical research
Feb 01, 2011 |
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Metabolic syndrome found in 52 percent of patients after liver transplantation
Researchers from Israel have determined that more than half of liver transplant recipients develop post-transplantation metabolic syndrome (PTMS), placing them at greater risk for cardiovascular disease. Prior to transplantation ...
Medicine & Health / Diseases, Conditions, Syndromes
Jan 06, 2011 |
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SRC-1 controls liver's 'sweet spot' for glucose production
SRC-1 (steroid receptor coactivator) orchestrates glucose production in the liver, regulating the activity of a cascade of enzymes that turns sugar production on and off in the liver, said Baylor College of Medicine and Duke ...
Medicine & Health / Medical research
Nov 30, 2010 |
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Scientists identify proteins that ensure iron balance
(PhysOrg.com) -- Most organisms need iron to survive, but too much iron is toxic, and can cause fatal organ failure. The same is true inside cells, where iron balance must also be maintained. In a study published today in ...
Aug 03, 2010 |
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High fructose, trans fats lead to significant liver disease, says study
Scientists at Cincinnati Children's Hospital Medical Center have discovered that a diet with high levels of fructose - levels equivalent to that in high fructose corn syrup - and of trans fats not only increases obesity, ...
Medicine & Health / Medical research
Jun 22, 2010 |
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Hepatitis C virus interference via hepcidin synthesis
Iron overload, a common feature of chronic liver disorders, has been linked with oxidative DNA damage, insulin resistance and liver steatosis, and with triggering of hepatic stellate cells thus inducing liver fibrosis. Recently, ...
Medicine & Health / Diseases, Conditions, Syndromes
Apr 12, 2010 |
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New data show breakthrough microRNA-targeted therapy holds promise as new treatment for hepatitis C
A study published online in this week's Science shows that SPC3649, a breakthrough microRNA-targeted therapy developed by Santaris Pharma A/S, holds promise as a novel treatment for patients infected with the Hepatitis C viru ...
Medicine & Health / Diseases, Conditions, Syndromes
Dec 03, 2009 |
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New data emerges on liver transplant survival rates
Researchers at the University of Miami School of Medicine compared the outcomes of cirrhotic patients who underwent liver transplants for nonalcoholic steatohepatitis (NASH) versus alcoholic liver disease (ETOH) and found ...
Medicine & Health / Diseases, Conditions, Syndromes
Nov 25, 2009 |
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The correlation between incidental NAFLD and carotid atherosclerosis
Nonalcoholic fatty liver disease (NAFLD) is often caused by abdominal obesity, which is also one of the main causes of insulin resistance and metabolic syndrome. The latter, in turn, is an important cardiovascular risk factor, ...
Medicine & Health / Diseases, Conditions, Syndromes
Oct 23, 2009 |
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Alcohol tolerance 'switch' found
Researchers at North Carolina State University have found a genetic "switch" in fruit flies that plays an important role in making flies more tolerant to alcohol.
Oct 21, 2009 |
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