An interdisciplinary team of scientists from Cologne, Heidelberg and Munich have discovered a new function of a well-known enzyme. The signal peptidase complex in the endoplasmic reticulum cleaves faulty membrane proteins ...
Cell & Microbiology
Dec 1, 2022
0
102
The mechanism by which fat-related molecules called lipids regulate pacemaker ion channel proteins, which help control the heart rhythm, has been revealed in a study from researchers at Weill Cornell Medicine.
Molecular & Computational biology
Nov 9, 2022
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33
A new study published in the journal Science Advances sheds light on how Gram-negative bacteria like E. coli construct their outer membrane to resemble body armor, which has far-reaching implications for the development of ...
Biochemistry
Nov 3, 2022
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27
Cell membranes make up the exterior of all cells and are a basic structure found in most living organisms. But they can also help parasites survive in the human body, play an important part in cancer growth and enclose and ...
Cell & Microbiology
Oct 27, 2022
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12
Ferroptosis, an iron-dependent regulated cell death process driven by excessive lipid peroxides and membrane injury, can enhance cancer vulnerability to chemotherapy. Lipid peroxidation of unsaturated lipids (UL) in biological ...
Bio & Medicine
Oct 21, 2022
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13
Researchers at Duke-NUS Medical School and colleagues in Singapore have identified a protein that transports degraded membrane lipids out of lysosomes, cellular organelles that are the breakdown factories of cells. The findings, ...
Cell & Microbiology
Sep 27, 2022
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52
Glycosylphosphatidylinositol (GPI) anchoring is an important post-translational modification, which tethers non-transmembrane proteins to the outer leaflet of the plasma membrane (PM). It participates in many biological processes ...
Plants & Animals
Aug 29, 2022
0
18
NAC transcription factors (TFs) are involved in regulating complex signaling networks that respond to various abiotic stresses. However, it is unknown whether NAC TFs can negatively regulate fruit cold tolerance by regulating ...
Molecular & Computational biology
Aug 10, 2022
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33
Scientists at Utrecht University have discovered a new mechanism antibiotics use to kill bacteria. The antibiotic teixobactin uses a dual molecular strategy: it blocks the bacterial cell wall synthesis and destructs the cell ...
Cell & Microbiology
Aug 3, 2022
0
393
Epithelial cells, which line the surfaces and organs of the body, can protect themselves against cancer by removing unhealthy or abnormal cells through a mechanism known as "apical extrusion," where the damaged cells are ...
Cell & Microbiology
Jul 11, 2022
0
62
