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L-DOPA

L-DOPA (L-3,4-dihydroxyphenylalanine) is a chemical that is made and used as part of the normal biology of some animals and plants. Some animals including humans make it via biosynthesis from the amino acid L-tyrosine. L-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline) collectively known as catecholamines. L-DOPA can be manufactured and in its pure form is sold as a psychoactive drug with the INN levodopa; trade names include Sinemet, Parcopa, Atamet, Stalevo, Madopar, Prolopa, etc.). As a drug it is used in the clinical treatment of Parkinson's disease and dopamine-responsive dystonia.

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Non-dopaminergic drug preladenant reduces motor fluctuations in patients with Parkinson's disease

Preladenant, a non-dopaminergic medication, reduces off time in patients with Parkinson's disease receiving standard dopamine therapy, an international study led by the University of South Florida found.

Medicine & Health / Neuroscience

created Feb 10, 2011 | popularity not rated yet | comments 0

Parkinson's disease treatment strategies appear to have similar long-term effects on disability

Patients with early Parkinson disease appear to have similar overall levels of disability and quality of life six years after beginning treatment with either levodopa or a dopamine agonist, according to a report posted online ...

Medicine & Health / Neuroscience

created Mar 09, 2009 | popularity not rated yet | comments 0