Key protein linked to appetite and obesity in mice

Researchers from the Okinawa Institute of Science and Technology Graduate University (OIST) have identified a protein that plays a key role in how the brain regulates appetite and metabolism. Loss of the protein, XRN1, from ...

The melodious mouse that sings for sex

A small, brown mouse found in the forests of Central America bucks the rodent trend of conversing in high-pitched squeaks often inaudible to the human ear.

New discovery finds missing hormone in birds

University of Akron researchers discovered leptin in the mallard duck, peregrine falcon and zebra finch, marking the first time the hormone has been found in birds.

Researchers discover obesity-related hormone in fruit flies

Researchers have discovered in fruit flies a key metabolic hormone thought to be the exclusive property of vertebrates. The hormone, leptin, is a nutrient sensor, regulating energy intake and output and ultimately controlling ...

Leptin-controlled gene can reverse diabetes

Researchers have found that even a very little bit of the fat hormone leptin goes a long way when it comes to correcting diabetes. The hormone controls the activity of a gene known as IGFBP2 in the liver, which has antidiabetic ...

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Leptin

Leptin (Greek leptos meaning thin) is a 16 kDa protein hormone that plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. It is one of the most important adipose derived hormones. The Ob(Lep) gene (Ob for obese, Lep for leptin) is located on chromosome 7 in humans.

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