Cyclin-dependent kinase 1 (Cdk1) is a member of the Cdk family of enzymes which control the cell cycle. Philipp Kaldis at the A*STAR Institute of Molecular and Cell Biology and co-workers have now shown that Cdk1 plays a ...
Cell & Microbiology
Jun 20, 2012
0
0
For a sperm to fertilize an egg, the sperm must first mature in a man's epididymis. Now, an international team of researchers has identified a chain of events in which a protein secreted by the testis travels in the luminal ...
Cell & Microbiology
Jun 4, 2020
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141
University of California, Berkeley scientists have developed a quicker and more efficient method to alter the genes of mice with CRISPR-Cas9, simplifying a procedure growing in popularity because of the ease of using the ...
Biotechnology
May 27, 2016
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267
Genome editing using CRISPR/Cas system has enabled direct modification of the mouse genome in fertilized mouse eggs, leading to rapid, convenient, and efficient one-step production of knockout mice without embryonic stem ...
Biotechnology
May 1, 2015
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35
Research published in the October Molecular and Cellular Biology moves us closer to developing drugs that could mitigate diabetes.
Cell & Microbiology
Oct 21, 2011
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1
Deleting the receptor, not the protein ghrelin itself, turns up the body's fat-burning thermostat, giving aging mice an exothermic boost toward a svelte physique, researchers reported at the American Society of Cell Biology's ...
Cell & Microbiology
Dec 13, 2010
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0
What genes are responsible for the development of breast cancer? What are the brain cell mutations that lead to the onset of Alzheimer's? To find new therapies, scientists have to understand how diseases are triggered at ...
Biotechnology
Apr 2, 2013
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0
Knocking genes out of action allows researchers to learn what genes do by seeing what goes wrong without them. University of Utah biologists pioneered the field. Mario Capecchi won a Nobel Prize for developing knockout mice. ...
Biotechnology
Apr 25, 2010
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0
(PhysOrg.com) -- Skeletal muscle enables us to walk, run or play a musical instrument, but it also plays a crucial role in controlling disease. Rockefeller University scientists have now shown how a specific molecule in skeletal ...
Biochemistry
Jul 27, 2010
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0
RNA carries pieces of instructions encoded in DNA to coordinate the production of proteins that will carry out the work to be done in a cell. But the process isn't always straightforward. Chemical modifications to DNA or ...
Cell & Microbiology
Oct 31, 2018
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