Researchers from Tokyo Metropolitan University have shown that the protein Musashi-2 (Msi2) plays a key role in the regulation of mass and metabolic processes in skeletal muscle. They studied mice with the Msi2 gene knocked ...
Cell & Microbiology
Sep 11, 2023
0
8
DNA methylation is a major epigenetic modification that is crucial for mammalian development. For instance, DNA methylation is central to inexhaustible biological processes, such as gene regulation and cell fate decisions. ...
Cell & Microbiology
Apr 18, 2022
0
24
About 120 million unintended pregnancies occurred each year between 2015 and 2019 worldwide. While there are oral contraceptives for women, the development of oral contraceptives for men has not been successful. Now, a team ...
Molecular & Computational biology
Aug 23, 2021
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392
The body plan of an organism, crafted over millennia of evolutionary trial and error, is so exquisitely fine-tuned that even a subtle deviation can be detrimental to individual survival and reproductive success. Now, researchers ...
Evolution
Dec 16, 2020
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5
For a sperm to fertilize an egg, the sperm must first mature in a man's epididymis. Now, an international team of researchers has identified a chain of events in which a protein secreted by the testis travels in the luminal ...
Cell & Microbiology
Jun 4, 2020
0
141
RNA carries pieces of instructions encoded in DNA to coordinate the production of proteins that will carry out the work to be done in a cell. But the process isn't always straightforward. Chemical modifications to DNA or ...
Cell & Microbiology
Oct 31, 2018
0
18
University of Toronto researchers have identified a gene that determines whether the body will adapt to changing seasons.
Biotechnology
Apr 19, 2017
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19
University of California, Berkeley scientists have developed a quicker and more efficient method to alter the genes of mice with CRISPR-Cas9, simplifying a procedure growing in popularity because of the ease of using the ...
Biotechnology
May 27, 2016
0
267
Genome editing using CRISPR/Cas system has enabled direct modification of the mouse genome in fertilized mouse eggs, leading to rapid, convenient, and efficient one-step production of knockout mice without embryonic stem ...
Biotechnology
May 1, 2015
0
35
The proteins that underlie nearly all biological mechanisms are produced from RNA molecules transcribed from genetic sequences in DNA. However, a large proportion of transcribed RNA is not transcoded into proteins and appears ...
Cell & Microbiology
Jan 9, 2015
0
52
