News tagged with journal of organic chemistry
Efficient preparation of a set of potential glycosidase inhibitors
(Phys.org) -- In many biological and pathological processes, glycosidase enzymes attack glycosidic bonds in carbohydrates, glycoproteins, and glycolipids. The ability to modify or block these processes by ...
May 29, 2012 |
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Strategy discovered to activate genes that suppress tumors and inhibit cancer
(Medical Xpress) -- A team of scientists has developed a promising new strategy for "reactivating" genes that cause cancer tumors to shrink and die. The researchers hope that their discovery will aid in the ...
May 21, 2012 |
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Researchers discover method to unravel malaria's genetic secrets
The parasite that causes malaria is a genetic outlier, which has prevented scientists from discovering the functions of most of its genes. Researchers at National Jewish Health and Yale University School of Medicine have ...
Jan 25, 2012 |
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Uptake protein acts as zinc's doorway to the cell
(PhysOrg.com) -- A study to be published as the "Paper of the Week" in the Journal of Biological Chemistry this December details how zinc, an element fundamental to cell growth, enters the cell via zinc-s ...
Nov 22, 2010 |
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Researchers demonstrate green tea is effective in treating genetic disorder and types of tumors
A compound found in green tea shows great promise for the development of drugs to treat two types of tumors and a deadly congenital disease. The discovery is the result of research led by Principal Investigator, ...
Aug 15, 2011 |
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Eclectic enzymes: Easily modified building blocks for drug design
(PhysOrg.com) -- In the pursuit of biologically active compounds, it is often necessary to be able to control the stereochemistry at predefined positions in a molecular skeleton. The search for ways to prepare ...
Sep 02, 2010 |
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The Key that Fits: New Technique To Trace Disease-Related Agents
(PhysOrg.com) -- In the development of new drugs, photoaffinity labels (PALs) are a versatile tool to investigate the interaction between a receptor and a drug or a ligand. Researchers working with Stephanie Grond at the ...
Mar 05, 2010 |
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Gold nanoparticles create visible-light catalysis in nanowires
(PhysOrg.com) -- A scientist at the Argonne National Laboratory has created visible-light catalysis, using silver chloride nanowires decorated with gold nanoparticles, that may decompose organic molecules ...
Jun 15, 2010 |
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Avoid the fallout: New ligands for nuclear waste treatment
(PhysOrg.com) -- Storage and containment of the "nuclear legacy", the highly radiotoxic residues from spent nuclear reactors is a pressing problem for the nuclear power industry that must be solved if nuclear ...
Jan 24, 2012 |
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Written in Red: Red-Emitting Dyes for Optical Microscopy and Nanoscopy
(PhysOrg.com) -- Far-field optical nanoscopy methods, especially STED (stimulated emission depletion), pose very strict and, at times, contradictory requirements on the utilized fluorescent markers. Photostable ...
Jul 07, 2010 |
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The secret jungles of ancient France
(PhysOrg.com) -- Ah, Paris. Land of the Eiffel Tower, delicious French bread and... tropical rainforests? Sacrebleu! It seems unlikely, but scientists have discovered evidence that France may have been a hot, wet tropical ...
Jul 16, 2009 |
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A New Way of Treating the Flu
(PhysOrg.com) -- What happens if the next big influenza mutation proves resistant to the available anti-viral drugs? This question was presenting itself to scientists and health officials recently at the World ...
Jul 06, 2009 |
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A new way of the treating the flu: Approach targets both the H and N portions of the virus
(PhysOrg.com) -- What happens if the next big influenza mutation proves resistant to the available anti-viral drugs? This question is presenting itself right now to scientists and health officials this week ...
May 19, 2009 |
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Take your vitamins: Tocopherol derivatives as new dioxin receptor antagonists
(PhysOrg.com) -- When reactive oxygen species (ROS) hit the body, vitamin E helps to prevent damage to tissues and cells by acting as an antioxidant. The health benefits of vitamin E are numerous, and in fact, ...
Mar 18, 2011 |
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What's the label? Helping to unravel the role of nature in biosynthetic pathways
(PhysOrg.com) -- Terpenoids are a very large and diverse class of compounds which includes certain hormones, flavors, and drugs, such as steroids, cinnamon or menthol, and antibacterials. They are found in ...
May 17, 2011 |
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