Related topics: brain · cells · nerve cells · cell membrane

3-D atomic structure of TRPML1 ion channel published

UT Southwestern Medical Center researchers today published a 3-D atomic structure of the ion channel found in mammals that is implicated in a rare, inherited neurodegenerative disease in humans. The work marks the first ...

Molecular volume control

About two years ago, scientists from the University of Würzburg discovered that a certain class of receptors is capable of perceiving mechanical stimuli. Now they have begun to unravel the molecular mechanisms behind the ...

Probing the pores in membrane vesicles

Ion channels in the membrane vesicles that mediate intracellular protein transport play a crucial role in cell physiology. A method developed by an Ludwig-Maximilians-Universitaet (LMU) in Munich team now allows them to be ...

New insight into a central biological dogma on ion transport

New research results from Aarhus University and New York University show how active transport of potassium can be achieved by a membrane protein complex that has roots in both ion pump and ion channel super-families. The ...

Flexibility is key in mechanism of biological self-assembly

A new study has modeled a crucial first step in the self-assembly of cellular structures such as drug receptors and other protein complexes, and found that the flexibility of the structures has a dramatic impact on how fast ...

One synthetic molecule, two doorways into cell

Shuhei Furukawa from Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) and colleagues in Japan synthesised polyhedral-shaped porous molecules that rotate in a double layer of lipids, exposing different-shaped ...

Adaptor proteins control ion channel gating mechanism

Ion channels are proteins that form pores in cellular membranes, which can be opened and shut like lock gates to allow the passage of electrically charged atoms (ions). Members of this class of proteins are crucial components ...

Malaria mosquitos sensitive to horseradish

Researchers at Lund University in Sweden have taken an important step on the road to understanding the underlying mechanism of how and why animals can feel pain in connection with cold or heat. However, according to the study, ...

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