Study decodes structure of protein complex active in DNA repair

The human body, if anything, is economical. The fittingly named and abundant protein ubiquitin is best known for its central role in recycling misfolded proteins. But it has other functions, too - the addition or removal ...

Scientists sleuth out proteins involved in Crohn's disease

(Phys.org) —University of Delaware researchers have identified a protein, hiding in plain sight, that acts like a bodyguard to help protect and stabilize another key protein, that when unstable, is involved in Crohn's disease. ...

Research reveals how key controller protein is switched on

New research has uncovered how a complex protein pivotal in the development of cancer, viral infection and autoimmune diseases is activated. The discovery answers a key question about one of the most widely-researched proteins ...

Gene prevents buildup of misfolded cell proteins

(Phys.org) —Much like how a snowplow is needed to clear streets of heavy snow, cells employ a set of genes to clear away misfolded proteins, to prevent them from accumulating and destroying the cell.

Birds appear to lack important anti-inflammatory protein

From bird flu to the West Nile virus, bird diseases can have a vast impact on humans. Thus, understanding bird immune systems can help people in a variety of ways, including protecting ourselves from disease and protecting ...

Typhoid Mary case may be cracked, a century later

When Typhoid Mary died in 1938, in medical exile on a tiny New York island, she took untold numbers of Salmonella typhi to her grave. No one knew how the bacteria managed to thrive and not kill her.

Teamwork against mutant free riders

(Phys.org)—Pathogenic salmonellae rely on a division of labour: some of them see to the common wellbeing, while others are able to stand up to free rider salmonellae better. This teamwork bears certain similarities to that ...

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