Use of antivirals in retrovirus-infected cats

A number of antiviral drugs are licensed and widely used for the treatment of specific viral infections in humans. Potential new agents are also being investigated that it is hoped will overcome limitations of the current ...

Scientists unravel elusive structure of HIV protein

HIV, or human immunodeficiency virus, is the retrovirus that leads to acquired immunodeficiency syndrome or AIDS. Globally, about 35 million people are living with HIV, which constantly adapts and mutates creating challenges ...

Trapping and watching motile cells

A new approach enables rapid characterization of living suspension cells in 4 dimensions while they are immobilized and manipulated within optical traps.

HIV virulence depends on where virus inserts itself in host DNA

The human immunodeficiency virus (HIV) can insert itself at different locations in the DNA of its human host - and this specific integration site determines how quickly the disease progresses, report researchers at KU Leuven's ...

Surges in latent infections: Mathematical analysis of viral blips

Recurrent infection is a common feature of persistent viral diseases. It includes episodes of high viral production interspersed by periods of relative quiescence. These quiescent or silent stages are hard to study with experimental ...

Mathematical models to better combat HIV

The first few hours to days following exposure to human immunodeficiency virus (HIV) can be of critical importance in determining if infection occurs in a patient. But the low numbers of viruses and infected cells at this ...

Mutation breaks HIV's resistance to drugs

The human immunodeficiency virus (HIV) can contain dozens of different mutations, called polymorphisms. In a recent study an international team of researchers, including MU scientists, found that one of those mutations, called ...

New drug-screening method yields long-sought anti-HIV compounds

Scientists at The Scripps Research Institute have used a powerful new chemical-screening method to find compounds that inhibit the activity of human immunodeficiency virus (HIV), the virus that causes AIDS. Unlike existing ...

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