Related topics: immune system

The enemy within: How pathogens spread unrecognized in the body

Some pathogens hide inside human cells to enhance their survival. Researchers at the University of Basel, have uncovered a unique tactic certain bacteria use to spread in the body without being detected by the immune system. ...

Key protein regulates immune response to viruses in mammal cells

Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development ...

Insect immune insights: Researchers unveil immune system dynamics

A paper published in PLoS Pathogens, titled "Mapping the functional form of the trade-off between infection resistance and reproductive fitness under dysregulated immune signaling," delves into the microscopic realm and unravels ...

Must mRNA be cloaked in a lipid coat to serve as a vaccine?

The Uchida Laboratory of Innovation Center of NanoMedicine has demonstrated that intradermal administration of mRNA alone (naked mRNA) without protection by nanoparticles induced robust vaccination against SARS CoV-2, a virus ...

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Immunity (medical)

Immunity is a biological term that describes a state of having sufficient biological defenses to avoid infection, disease, or other unwanted biological invasion. Immunity involves both specific and non-specific components. The non-specific components act either as barriers or as eliminators of wide range of pathogens irrespective of antigenic specificity. Other components of the immune system adapt themselves to each new disease encountered and are able to generate pathogen-specific immunity.

Adaptive immunity is often sub-divided into two major types depending on how the immunity was introduced. Naturally acquired immunity occurs through contact with a disease causing agent, when the contact was not deliberate, whereas artificially acquired immunity develops only through deliberate actions such as vaccination. Both naturally and artificially acquired immunity can be further subdivided depending on whether immunity is induced in the host or passively transferred from a immune host. Passive immunity is acquired through transfer of antibodies or activated T-cells from an immune host, and is short lived, usually lasts only a few months, whereas active immunity is induced in the host itself by antigen, and lasts much longer, sometimes life-long. The diagram below summarizes these divisions of immunity.

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