Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable ...
Biochemistry
Dec 8, 2023
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8
A central component of the human immune system, the NLRP3 inflammasome plays an important role in fighting off infections. However, its chronic activation is also implicated in a variety of common diseases, such as Alzheimer's, ...
Molecular & Computational biology
Dec 8, 2023
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21
Existing flu vaccines provide only limited, seasonal protection because they target highly changeable proteins on the virus. Scripps Research scientists have now designed a vaccine that should work broadly against influenza ...
Bio & Medicine
Dec 8, 2023
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51
Researchers at Kanazawa University report in the Journal of Physical Chemistry Letters high-speed atomic force microscopy studies that shed light on the possible role of the open reading frame 6 (ORF6) protein in COVID-19 ...
Biochemistry
Nov 29, 2023
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59
RNA (ribonucleic acid), which is made up of ribonucleotides, is a molecule found in all living organisms. RNA is thought to have probably preceded DNA in primordial life billions of years ago. RNA was eventually replaced ...
Molecular & Computational biology
Nov 27, 2023
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1
The human immune system is based on cells that communicate with each other via signaling molecules known as cytokines and chemokines. One of these signaling molecules is the protein MIF (macrophage migration inhibitory factor). ...
Biochemistry
Nov 24, 2023
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49
Scientists have found that extracellular calcium mediates the activation of a membrane protein that waves the flag signaling cell death.
Cell & Microbiology
Sep 14, 2023
0
4
Imagine a dark room packed full of furniture. Now imagine moving through it to get to the other side, using only your toe tips for guidance. While it may seem challenging (or unspeakably tedious) to us, this is a task that ...
Cell & Microbiology
Sep 13, 2023
0
14
How the expression of Cas proteins in bacterial CRISPR-Cas immune system adapts to the constantly changing CRISPR structures and crRNA expression levels has been a long-standing unresolved question.
Cell & Microbiology
Sep 8, 2023
0
32
Short-lived proteins control gene expression in cells to carry out a number of vital tasks, from helping the brain form connections to helping the body mount an immune defense. These proteins are made in the nucleus and are ...
Cell & Microbiology
Aug 24, 2023
0
294
