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The hypothalamus predates the origin of vertebrates

The hypothalamus is involved during the coordination of neuroendocrine functions in vertebrates and their evolutionary origin can be described using integrated transcriptome or connectome brain maps of swimming tadpoles of ...

A unique on-off switch for hormone production

Weizmann scientists have revealed a new kind of on-off switch in the brain for regulating the production of a main biochemical signal from the brain that stimulates cortisol release in the body.

Hypothalamus

The hypothalamus is a portion of the brain that contains a number of small nuclei with a variety of functions. One of the most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland (hypophysis). The hypothalamus, (from Greek ὑποθαλαμος = under the thalamus) is located below the thalamus, just above the brain stem. In the terminology of neuroanatomy, it forms the ventral part of the diencephalon. All vertebrate brains contain a hypothalamus. In humans, it is roughly the size of an almond.

The hypothalamus is responsible for certain metabolic processes and other activities of the Autonomic Nervous System. It synthesizes and secretes neurohormones, often called hypothalamic-releasing hormones, and these in turn stimulate or inhibit the secretion of pituitary hormones. The hypothalamus controls body temperature, hunger, thirst, fatigue, and circadian cycles.

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