News tagged with humanized mouse
Study dusts sugar coating off little-known regulation in cells
In Alzheimer's disease, brain neurons become clogged with tangled proteins. Scientists suspect these tangles arise partly due to malfunctions in a little-known regulatory system within cells. Now, researchers have dramatically ...
Apr 16, 2012 |
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New type of extra-chromosomal DNA discovered
(PhysOrg.com) -- A team of scientists from the University of Virginia and University of North Carolina in the US have discovered a previously unidentified type of small circular DNA molecule occurring outside ...
Mar 09, 2012 |
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Autistic mice act a lot like human patients
UCLA scientists have created a mouse model for autism that opens a window into the biological mechanisms that underlie the disease and offers a promising way to test new treatment approaches.
Sep 29, 2011 |
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Mouse genetic blueprint developed
Researchers have developed a valuable mouse genetic blueprint that will accelerate future research and understanding of human genetics. The international team, led by researchers at the Wellcome Trust Sanger ...
Sep 14, 2011 |
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A knockout resource for mouse genetics
An international consortium of researchers report today in Nature that they have knocked out almost 40 per cent of the genes in the mouse genome. The completed resource will power studies of gene activity in models of hum ...
Jun 15, 2011 |
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Protein found to be the link missing between HPV infection and cervical cancer development
Most women are infected with human papillomavirus (HPV), which can cause cervical cancer - yet few develop the cancer. Now researchers at Georgetown Lombardi Comprehensive Cancer Center, a part of Georgetown University Medical ...
Apr 05, 2011 |
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Uncovering the trail behind growing too old, too soon
Scientists from A*STAR's Institute of Medical Biology (IMB) in Singapore and the University of Hong Kong's Department of Medicine have produced the world's first human cell model of progeria, a disease resulting in severe ...
Medicine & Health / Medical research
Jan 24, 2011 |
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Unlikely genetic suspect implicated in common brain defect
A genetic search that wound its way from patients to mouse models and back to patients has uncovered an unlikely gene critically involved in a common birth defect which causes mental retardation, motor delays ...
Aug 09, 2009 |
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Mouse Model Provides Clues to Human Language Development
Scientists of the German Mouse Clinic at Helmholtz Zentrum Muenchen (Germany) have made a major contribution to understanding human language development. Using a comprehensive screening method, they studied a mouse model ...
Medicine & Health / Medical research
Jun 24, 2009 |
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Researchers discover new glucose-regulating protein linked with diabetes
Researchers at the University of California, San Francisco, and collaborators at Harvard Medical School have linked a specialized protein in human muscles to the process that clears glucose out of the bloodstream, shedding ...
May 28, 2009 |
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Meet the complete mouse -- whole mouse genome sequence published
Are you a man or a mouse? A new paper, published in this week's issue of PLoS Biology, explores exactly what distinguishes our genome from that of the lab mouse. In the first comprehensive comparison betwee ...
May 27, 2009 |
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Why do people with Down syndrome have less cancer?
Most cancers are rare in people with Down syndrome, whose overall cancer mortality is below 10 percent of that in the general population. Since they have an extra copy of chromosome 21, it's been proposed that people with ...
Medicine & Health / Medical research
May 20, 2009 |
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Humanized mouse infected with HIV vaginally and rectally allows testing
The "humanized mouse" developed by Dr. J. Victor Garcia-Martinez has allowed the University of Texas Southwestern physician-scientist to conduct HIV/AIDS studies that would have been impossible without such a small animal ...
Medicine & Health / HIV & AIDS
Apr 20, 2009 |
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Scientists develop mouse models of leukemia that predict response to chemotherapy
Being able to accurately predict how a given cancer will respond to chemotherapy would spare patients with non-responsive tumors the burden of undergoing toxic and ultimately unhelpful treatment. Just as important, knowing ...
Mar 31, 2009 |
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